Immunotolerance in Endometrial Cancer and at the Maternal-fetal Interface: Immunological Profiling of the Tumor Microenvironment in Risk Stratification of Recurrence
Recruiting
- Conditions
- Endometrial Cancer
- Interventions
- Diagnostic Test: tissue samples (healthy and tumor taken from the same patient) and tissue samples (decidualized endometrium and trophoblast taken from it patient)
- First Posted Date
- 2024-02-08
- Last Posted Date
- 2024-05-31
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06250010
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Biomarkers of Efficacy and Tolerability of Sacituzumab-Govitecan in the Treatment of Patients With Triple-negative Breast Cancer in the Metastatic Phase: Prospective Multicenter Real-world Study
Recruiting
- Conditions
- Breast Cancer
- Interventions
- Other: data collection
- First Posted Date
- 2024-02-02
- Last Posted Date
- 2024-03-25
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 60
- Registration Number
- NCT06240195
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Generation of Lung Tumor Organoids From Patients Undergoing Diagnostic Bronchoscopy
Not Applicable
Recruiting
- Conditions
- Generation of Lung Cancer Organoids
- Interventions
- Procedure: Biopsies performed via bronchoscopy
- First Posted Date
- 2024-02-02
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06239584
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
Phase 2
Recruiting
- Conditions
- Breast CancerBreast Neoplasms
- Interventions
- Radiation: Ten-fraction hypofractionated breast radiotherapy with 43 Gy simultaneous integrated bed boostRadiation: Ten-fraction hypofractionated breast radiotherapy with 40 Gy simultaneous integrated bed boost
- First Posted Date
- 2024-01-25
- Last Posted Date
- 2024-01-25
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 180
- Registration Number
- NCT06224244
- Locations
- 🇮🇹
Regina Elena Cancer Institute, Rome, Lazio, Italy
Analysis of HPV and Biomarkers Present in the Biological Fluids of Patients Suffering From Head and Neck Cancer as a Non-invasive Strategy for Detecting Recurrence
Recruiting
- Conditions
- Head and Neck Tumors
- First Posted Date
- 2024-01-25
- Last Posted Date
- 2024-01-26
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 283
- Registration Number
- NCT06224166
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer
Active, not recruiting
- Conditions
- Gastric CancerDNA Damage
- Interventions
- Diagnostic Test: investigated biomarkers regarding the efficacy of first-line chemotherapy
- First Posted Date
- 2024-01-12
- Last Posted Date
- 2024-01-18
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 167
- Registration Number
- NCT06204523
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Radiological Evaluation of 3D Printed Porous Collars in Hip and Knee Resection Prostheses: Pilot Study.
Recruiting
- Conditions
- Bone Tumor
- First Posted Date
- 2023-12-22
- Last Posted Date
- 2024-03-22
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06180525
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Validation Study of a Serum-miRNA Signature in Glioma Patients.
Active, not recruiting
- Conditions
- Biomarker
- Interventions
- Diagnostic Test: Validation of miRNA-serum signatures associated with IDH1 status
- First Posted Date
- 2023-12-21
- Last Posted Date
- 2023-12-21
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 30
- Registration Number
- NCT06178692
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer
Recruiting
- Conditions
- PREDICTIVE BIOMARKERSEvaluation of HPV-specific E5 Transcript Expression in a Cohort of Patients With HPV-associated OPCHPV 16 Positive Oropharyngeal Tumors (OPC)
- Interventions
- Diagnostic Test: HPV-ASSOCIATED OROPHARYNGEAL CANCER
- First Posted Date
- 2023-10-24
- Last Posted Date
- 2023-10-24
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 20
- Registration Number
- NCT06097936
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers
Recruiting
- Conditions
- Quality of LifeLarynx Cancer
- Interventions
- Diagnostic Test: to assess the voice perception of the patient undergoing phonatory prosthesis placement surgery by evaluating the optimal score (>30) in terms of VHI.
- First Posted Date
- 2023-10-17
- Last Posted Date
- 2023-10-17
- Lead Sponsor
- Regina Elena Cancer Institute
- Target Recruit Count
- 31
- Registration Number
- NCT06086119
- Locations
- 🇮🇹
"Regina Elena" National Cancer Institute, Rome, Italy
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