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Prothena Biosciences Ltd.

🇮🇪Ireland
Ownership
Subsidiary
Employees
-
Market Cap
-
Website
http://www.prothena.com

Clinical Trials

8

Active:0
Completed:3

Trial Phases

3 Phases

Phase 1:2
Phase 2:3
Phase 3:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (7 trials with phase data)• Click on a phase to view related trials

Phase 2
3 (42.9%)
Phase 1
2 (28.6%)
Phase 3
2 (28.6%)

Phase 1 Study of PRX019 in Healthy Adult Volunteers

Phase 1
Recruiting
Conditions
Healthy Participants Study
Interventions
Drug: Placebo
First Posted Date
2024-11-21
Last Posted Date
2024-11-21
Lead Sponsor
Prothena Biosciences Ltd.
Target Recruit Count
48
Registration Number
NCT06699680
Locations
🇺🇸

Local Institution, Los Alamitos, California, United States

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis

Phase 3
Terminated
Conditions
Light Chain (AL) Amyloidosis
Interventions
Other: Placebo
Drug: Standard of Care Chemotherapy
First Posted Date
2021-07-22
Last Posted Date
2025-07-08
Lead Sponsor
Prothena Biosciences Ltd.
Target Recruit Count
208
Registration Number
NCT04973137
Locations
🇺🇸

Yale Cancer Center, North Haven, Connecticut, United States

🇺🇸

Smilow Cancer Hospital Care Center at Trumbull, Trumbull, Connecticut, United States

🇺🇸

MedStar Georgetown University Hospital, Washington, District of Columbia, United States

and more 106 locations

Study in Subjects With Light Chain (AL) Amyloidosis

Phase 2
Terminated
Conditions
AL Amyloidosis
Interventions
First Posted Date
2017-05-15
Last Posted Date
2019-03-26
Lead Sponsor
Prothena Biosciences Ltd.
Target Recruit Count
80
Registration Number
NCT03154047
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Colorado Blood Cancer Institute, Denver, Colorado, United States

🇺🇸

Mayo Clinic Hospital - Florida, Jacksonville, Florida, United States

and more 31 locations

The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis

Phase 2
Completed
Conditions
AL Amyloidosis
Interventions
Drug: Placebo
First Posted Date
2015-12-17
Last Posted Date
2019-04-05
Lead Sponsor
Prothena Biosciences Ltd.
Target Recruit Count
129
Registration Number
NCT02632786
Locations
🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

Stanford Cancer Institute (SCI), Stanford, California, United States

🇺🇸

Colorado Blood Cancer Institute, Denver, Colorado, United States

and more 37 locations

Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis

Phase 2
Terminated
Conditions
AL Amyloidosis
Interventions
First Posted Date
2015-11-24
Last Posted Date
2019-05-16
Lead Sponsor
Prothena Biosciences Ltd.
Target Recruit Count
34
Registration Number
NCT02613182
Locations
🇺🇸

Stanford Cancer Institute (SCI), Stanford, California, United States

🇺🇸

Tufts Medical Center, Boston, Massachusetts, United States

🇺🇸

Karmanos Cancer Institute, Detroit, Michigan, United States

and more 2 locations
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