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CatalYm GmbH

CatalYm GmbH logo
🇩🇪Germany
Ownership
Holding
Established
2016-01-01
Employees
11
Market Cap
-
Website
http://www.catalym.com

Clinical Trials

7

Active:4
Completed:0

Trial Phases

3 Phases

Phase 1:4
Phase 2:1
Not Applicable:2

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (7 trials with phase data)• Click on a phase to view related trials

Phase 1
4 (57.1%)
Not Applicable
2 (28.6%)
Phase 2
1 (14.3%)

Visugromab in Cachexia International Trial

Not Applicable
Not yet recruiting
Conditions
Cancer-associated Cachexia
Interventions
Drug: Visugromab (CTL-002)
Drug: Placebo
First Posted Date
2025-08-08
Last Posted Date
2025-08-08
Lead Sponsor
CatalYm GmbH
Target Recruit Count
518
Registration Number
NCT07112196

Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC

Not Applicable
Not yet recruiting
Conditions
Metastatic Non-Squamous Non-Small Cell Lung Cancer
Adult Solid Tumor
Interventions
First Posted Date
2025-08-01
Last Posted Date
2025-08-01
Lead Sponsor
CatalYm GmbH
Target Recruit Count
107
Registration Number
NCT07098988
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

A multi-center Phase 2 study of neoadjuvant immunotherapy in combination with the anti-GDF-15 antibody visugromab (CTL-002) for the treatment of muscle invasive bladder cancer

Phase 2
Active, not recruiting
Conditions
Muscle invasive bladder cancer set to undergo radical cystectomy who cannot receive or refuse to receive cisplatin-based chemotherapy
First Posted Date
2023-09-28
Last Posted Date
2025-09-02
Lead Sponsor
CatalYm GmbH
Target Recruit Count
31
Registration Number
2024-513957-55-00
Locations
🇮🇹

IRCCS Ospedale San Raffaele Hospital Vita-Salute San Raffaele University, Milan, Italy

🇮🇹

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

🇮🇹

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC Oncologia Medica, Roma, Italy

and more 1 locations

First-in-Human Study of the GDF-15 Neutralizing Antibody Visugromab (CTL-002) in Patients With Advanced Cancer (GDFATHER)

Phase 1
Active, not recruiting
Conditions
Solid Tumor, Adult
First Posted Date
2021-01-26
Last Posted Date
2024-08-09
Lead Sponsor
CatalYm GmbH
Target Recruit Count
274
Registration Number
NCT04725474
Locations
🇩🇪

Universitätsklinikum Essen, Westdeutsches Tumorzentrum, Innere Klinik und Poliklinik, Essen, Germany

🇩🇪

Universitätsklinikum Frankfurt, Medizinische Klinik I, Frankfurt am Main, Germany

🇩🇪

Universitätsklinikum Würzburg, Comprehensive Cancer Center, Würzburg, Germany

and more 10 locations

News

CatalYm's Visugromab Shows Promise in Enhancing Antibody-Drug Conjugate Efficacy by Blocking GDF-15

New preclinical data reveals that visugromab, CatalYm's GDF-15-neutralizing antibody, significantly enhances the anti-tumor activity of antibody-drug conjugates (ADCs) in multiple solid tumor models.

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