Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma

计划入组 135 人 · 首次发布于 2025 年 3 月 26 日

Based on SAC's regulation mechanism of E3 ligase APC/CCDC20 to study the effect and mechanism of electroacupuncture on egg aging

Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML

计划入组 24 人 · 首次发布于 2026 年 1 月 21 日

E3 ubiquitin ligase based protein degradation

Helios cereblon E3 ligase modulator (solid tumors)

E3-ubiquitin ligase Cbl-b inhibitors (cancer)

C4 Therapeutics

United States

CEREBOS PACIFIC LIMITED

Singapore

Ligand Pharmaceuticals

United States

Bavdegalutamide (ARV-110) Shows Promise as AR Degrader in Preclinical Prostate Cancer Models

Identification and Characterization of Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) in Disease Regulation

AbbVie and Neomorph Forge $1.64 Billion Molecular Glue Degrader Partnership for Oncology and Immunology