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The Study of Safety and Preliminary Efficacy of Aleeto in Patients with MultIple System Atrophy

Early Phase 1
Not yet recruiting
Conditions
Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Multiple System Atrophy, MSA
Interventions
Drug: Aleeto
First Posted Date
2025-01-09
Last Posted Date
2025-01-09
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
20
Registration Number
NCT06765733
Locations
🇨🇳

Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System

Conditions
Polyneuropathy
Alpha-Synucleinopathy
Lewy Body Disease
Parkinson Disease (PD)
Lewy Body Dementia (LBD)
Multiple System Atrophy
Autonomic Failure
Cardiac Imaging
Rapid Eye Movement Sleep Behavior Disorder
REM Sleep Behavior Disorder (iRBD)
First Posted Date
2024-12-20
Last Posted Date
2025-01-08
Lead Sponsor
University of Aarhus
Target Recruit Count
100
Registration Number
NCT06745011
Locations
🇩🇰

Institute of Clinical Medicine, Aarhus University, Aarhus, Jutland, Denmark

[18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients

Not yet recruiting
Conditions
α-synucleinopathy
Parkinson's Disease (PD)
Multiple System Atrophy
Rapid Eye Movement Sleep Behavior Disorder
PET
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Ruijin Hospital
Target Recruit Count
35
Registration Number
NCT06738862
Locations
🇨🇳

Department of neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

A Trial of Lu AF82422 in Participants With Multiple System Atrophy (MSA)

Phase 3
Recruiting
Conditions
Multiple System Atrophy
Interventions
Drug: Lu AF82422
Drug: Placebo
First Posted Date
2024-11-26
Last Posted Date
2025-01-09
Lead Sponsor
H. Lundbeck A/S
Target Recruit Count
360
Registration Number
NCT06706622
Locations
🇺🇸

Parkinson's Disease And Movement Disorder Center Of Boca Raton, Boca Raton, Florida, United States

🇺🇸

CenExel Rocky Mountain Clinical Research, LLC, Englewood, Colorado, United States

🇺🇸

QUEST Research Institute, Farmington Hills, Michigan, United States

and more 1 locations

Autologous SuraL NervE Grafting to the Substantia NigrA in Patients with Synuclienopathies

Phase 1
Not yet recruiting
Conditions
Multiple System Atrophy
Parkinsons Disease
First Posted Date
2024-11-12
Last Posted Date
2024-11-12
Lead Sponsor
Craig van Horne, MD, PhD
Target Recruit Count
7
Registration Number
NCT06683365
Locations
🇺🇸

University of Kentucky, Lexington, Kentucky, United States

Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases

Phase 1
Recruiting
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Alzheimer's Disease(AD)
Multiple System Atrophy, MSA
Interventions
Biological: Autologous Human Polyclonal Regulatory T Cells Injection (NP001 Cell Injection)
First Posted Date
2024-11-04
Last Posted Date
2024-11-04
Lead Sponsor
Novabio Therapeutics
Target Recruit Count
12
Registration Number
NCT06671236
Locations
🇺🇸

Ascension Via Christi Clinic, Wichita, Kansas, United States

🇨🇳

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

The CurePSP Genetics Program

Recruiting
Conditions
PSP
PSP - Progressive Supranuclear Palsy
Corticobasal Syndrome
Corticobasal Syndrome(CBS)
Corticobasal Degeneration Syndrome
Corticobasal Degeneration
Corticobasal Degeneration (CBD)
Corticobasal Syndrome (CBS)
MSA
MSA - Multiple System Atrophy
First Posted Date
2024-10-18
Last Posted Date
2024-11-05
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
1000
Registration Number
NCT06647641
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes

Recruiting
Conditions
Progressive Supranuclear Palsy
Cortico Basal Degeneration
Multiple System Atrophy
First Posted Date
2024-10-17
Last Posted Date
2024-10-17
Lead Sponsor
University Hospital Southampton NHS Foundation Trust
Target Recruit Count
198
Registration Number
NCT06645626
Locations
🇬🇧

Wessex Neurological Centre, Southampton, Hampshire, United Kingdom

HUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases

Phase 1
Not yet recruiting
Conditions
Alzheimer Disease
Parkinson Disease
Lewy Body Dementia
Multiple System Atrophy
Fronto-temporal Dementia
Interventions
Drug: hUC-MSC-sEV-001 nasal drops
First Posted Date
2024-09-23
Last Posted Date
2024-09-23
Lead Sponsor
Xuanwu Hospital, Beijing
Target Recruit Count
100
Registration Number
NCT06607900
Locations
🇨🇳

Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China

Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely

Not Applicable
Conditions
Parkinson Disease
Progressive Supranuclear Palsy(PSP)
Multiple System Atrophy
Interventions
Other: NeuraLight PD
Other: NeuraLight PSP
Other: NeuraLight MSA
Other: NeuraLight
First Posted Date
2024-09-19
Last Posted Date
2024-09-19
Lead Sponsor
NeuraLight
Target Recruit Count
40
Registration Number
NCT06597071
Locations
🇪🇸

Instituto de Biomedicina de Sevilla (IBiS), Sevilla, Spain

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