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Found 8 clinical trials|View Analysis
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Treating Early Stage Diabetic Retinopathy

Early Phase 1
Conditions
Diabetic Retinopathy
Interventions
Drug: Sinemet CR
Drug: placebo
First Posted Date
2021-11-24
Last Posted Date
2024-05-31
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
244
Registration Number
NCT05132660
Locations
🇺🇸

Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia, United States

Study to Assess Pharmacokinetics of Accordion Pill Carbidopa-Levodopa Compared to Immediate Release Carbidopa-Levodopa in Parkinson's Disease Patients

Phase 2
Conditions
Parkinson Disease
Interventions
Drug: Sinemet CR 25Mg-100Mg Extended-Release Tablet
Drug: Accordion Pill Carbidopa/Levodopa
First Posted Date
2018-07-03
Last Posted Date
2018-07-05
Lead Sponsor
Intec Pharma Ltd.
Target Recruit Count
12
Registration Number
NCT03576638

Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease

Phase 4
Completed
Conditions
Obstructive Sleep Apnea
Parkinson's Disease
Interventions
Drug: Sinemet CR
Drug: Placebo oral capsule
First Posted Date
2017-04-12
Last Posted Date
2024-03-13
Lead Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Target Recruit Count
36
Registration Number
NCT03111485
Locations
🇨🇦

McGill University Health Centre, Montreal, Quebec, Canada

The Effect of Dopamine on Diabetic Retinopathy

Phase 1
Completed
Conditions
Diabetes
Interventions
Drug: Low Dose Sinemet CR
Drug: High Dose Sinemet CR
Device: RETeval Electroretinogram (ERG) Testing
Other: Contrast Sensitivity Testing
Other: Visual Acuity Testing
First Posted Date
2016-03-11
Last Posted Date
2019-10-09
Lead Sponsor
Emory University
Target Recruit Count
60
Registration Number
NCT02706977
Locations
🇺🇸

Atlanta VA Medical Center, Atlanta, Georgia, United States

Pharmacokinetic-pharmacodynamic Interaction Between Each of Three Different Single Doses of BIA 9-1067 and a Single-dose of Controlled-release 100/25 mg Levodopa/Carbidopa

Phase 1
Completed
Conditions
Parkinson's Disease (PD)
Interventions
First Posted Date
2014-06-23
Last Posted Date
2015-01-21
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
12
Registration Number
NCT02169453
Locations
🇨🇦

Algorithme Pharma Inc, Mount-Royal, Quebec, Canada

The Effect of Pramipexole on Metabolic Network Activity Compared With Levodopa in Early Parkinson's Disease

Not Applicable
Completed
Conditions
Idiopathic Parkinson's Disease
Interventions
First Posted Date
2011-11-11
Last Posted Date
2015-10-21
Lead Sponsor
Huashan Hospital
Target Recruit Count
30
Registration Number
NCT01470859
Locations
🇨🇳

Huashan Hospital Affiliated to Fudan University, Shanghai, Shanghai, China

A Multiple-Dose Study of Sinemet® CR (Carbidopa/Levodopa) in Healthy Subjects

Completed
Conditions
Parkinson's Disease
First Posted Date
2007-04-17
Last Posted Date
2008-08-14
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
20
Registration Number
NCT00460954
Locations
🇨🇦

Local Institution, Toronto, Ontario, Canada

Study Of Cabaser and Sinemet CR For The Treatment Of Nighttime Symptoms Associated With Parkinson's Disease.

Phase 4
Terminated
Conditions
Parkinson Disease
First Posted Date
2005-09-15
Last Posted Date
2007-05-25
Lead Sponsor
Pfizer
Target Recruit Count
220
Registration Number
NCT00174239
Locations
🇪🇸

Pfizer Investigational Site, Sevilla, Spain

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