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Found 204 clinical trials|View Analysis
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Novel INPUT Screening Tool to Improve Illness Understanding in Patients with Metastatic or Incurable Lung Cancer

Not Applicable
Recruiting
Conditions
Lung Carcinoma
Metastatic Lung Carcinoma
Stage IV Lung Cancer AJCC V8
First Posted Date
2024-12-19
Last Posted Date
2025-01-07
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
100
Registration Number
NCT06743308
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Diclofenac for the Treatment of Patients with Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

Phase 2
Not yet recruiting
Conditions
Advanced Lung Non-Small Cell Carcinoma
Metastatic Lung Non-Small Cell Carcinoma
Stage III Lung Cancer AJCC V8
Stage IV Lung Cancer AJCC V8
Interventions
Biological: Atezolizumab
Procedure: Biospecimen Collection
Biological: Cemiplimab
Procedure: Computed Tomography
Drug: Diclofenac Potassium
Other: Electronic Health Record Review
Procedure: Magnetic Resonance Imaging
Biological: Nivolumab
Biological: Pembrolizumab
Procedure: Positron Emission Tomography
First Posted Date
2024-12-12
Last Posted Date
2024-12-12
Lead Sponsor
Emory University
Target Recruit Count
20
Registration Number
NCT06731270
Locations
🇺🇸

Emory University Hospital Midtown, Atlanta, Georgia, United States

🇺🇸

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

Grid Radiation Therapy for the Treatment of Stage IV Non-Small Cell Lung Cancer

Phase 2
Recruiting
Conditions
Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC V8
First Posted Date
2024-10-28
Last Posted Date
2024-11-25
Lead Sponsor
Mayo Clinic
Target Recruit Count
20
Registration Number
NCT06660407
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Assessing and Addressing Follow-up Care Needs That Will Facilitate Care Transitions for Cancer Survivors

Not Applicable
Not yet recruiting
Conditions
Stage I Lung Cancer
Stage II Lung Cancer
Stage III Lung Cancer
Stage IV Lung Cancer
First Posted Date
2024-10-23
Last Posted Date
2024-10-23
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
15
Registration Number
NCT06654245
Locations
🇺🇸

Atrium Health Wake Forest Baptist Comprehensive Cancer Center (AH-WFBCCC), Winston-Salem, North Carolina, United States

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

Phase 2
Not yet recruiting
Conditions
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Interventions
Procedure: Biospecimen Collection
Biological: Cemiplimab
Procedure: Computed Tomography
Drug: Dexamethasone
Drug: Docetaxel
Procedure: Magnetic Resonance Imaging
Biological: Ramucirumab
First Posted Date
2024-09-27
Last Posted Date
2024-09-27
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
378
Registration Number
NCT06616584

Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Phase 1
Recruiting
Conditions
Metastatic Lung Non-Small Cell Carcinoma
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC V8
Interventions
Biological: Atezolizumab
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Magnetic Resonance Imaging
Drug: Vismodegib
First Posted Date
2024-09-27
Last Posted Date
2025-01-03
Lead Sponsor
Dwight Owen
Target Recruit Count
24
Registration Number
NCT06616623
Locations
🇺🇸

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Recruiting
Conditions
Non Small Cell Lung Cancer
Epidermal Growth Factor Receptor Gene Mutation
Stage III Lung Cancer
Stage IV Lung Cancer
Interventions
First Posted Date
2024-08-05
Last Posted Date
2025-01-09
Lead Sponsor
PrECOG, LLC.
Target Recruit Count
538
Registration Number
NCT06538038
Locations
🇺🇸

UT Southwest, Dallas, Texas, United States

🇺🇸

Gundersen Lutheran Medical Foundation, La Crosse, Wisconsin, United States

🇺🇸

Mercy Clinic Fort Smith Communities, Fort Smith, Arkansas, United States

and more 11 locations

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

Phase 2
Recruiting
Conditions
Metastatic Malignant Neoplasm in the Leptomeninges
Metastatic Breast Carcinoma
Stage IV Lung Cancer AJCC v8
Metastatic Lung Non-Small Cell Carcinoma
Anatomic Stage IV Breast Cancer AJCC v8
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Other: Electronic Health Record Review
Procedure: Lumbar Puncture
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Radiation: Proton Beam Craniospinal Irradiation
Other: Survey Administration
Radiation: Volume Modulated Arc Therapy
First Posted Date
2024-07-24
Last Posted Date
2025-01-10
Lead Sponsor
University of Washington
Target Recruit Count
22
Registration Number
NCT06518057
Locations
🇺🇸

Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Phase 3
Recruiting
Conditions
Metastatic Breast Carcinoma
Metastatic Malignant Solid Neoplasm
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Digestive System Carcinoma
Stage IV Renal Cell Cancer AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Metastatic Melanoma
Metastatic Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Metastatic Malignant Neoplasm in the Brain
Interventions
Procedure: Computed Tomography
Radiation: Fractionated Stereotactic Radiation Therapy
Procedure: Magnetic Resonance Imaging
Radiation: Stereotactic Radiosurgery
First Posted Date
2024-07-15
Last Posted Date
2024-11-29
Lead Sponsor
NRG Oncology
Target Recruit Count
269
Registration Number
NCT06500455
Locations
🇺🇸

Banner University Medical Center - Tucson, Tucson, Arizona, United States

🇺🇸

University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

and more 57 locations

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

Phase 3
Not yet recruiting
Conditions
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Leptomeninges
Stage IV Lung Cancer AJCC v8
Metastatic Breast Carcinoma
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Radiation: Involved-Field Radiation Therapy
Procedure: Lumbar Puncture
Procedure: Magnetic Resonance Imaging
Procedure: Positron Emission Tomography
Radiation: Proton Beam Craniospinal Irradiation
Other: Quality-of-Life Assessment
First Posted Date
2024-07-15
Last Posted Date
2025-01-10
Lead Sponsor
NRG Oncology
Target Recruit Count
115
Registration Number
NCT06500481
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