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临床试验/CTRI/2024/05/067594
CTRI/2024/05/067594已完成2 期

Effect of Exercise Therapeutic Program on Physical Function, Depression and Quality of Life in Diabetic Nephropathy Patients: An Experimental Study

Nitte Institute of Physiotherapy1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2024年7月1日最近更新:

试验速览

阶段
2 期
状态
已完成
入组人数
15
试验地点
1
主要终点
Physical Function Test with 6 minute walk test, 30 seconds sit to stand test, Hand grip strength of non cannulated arm using dynamometer and Lower limb strength using dynamometer will be assessed.

研究概览

简要总结

End stage renal disease or Diabetic Nephropathy  or diabetic kidney disease is characterized by  decrease in urine protein. These patients experience cardiovascular complications which impair kidney function and general body deterioration . Because of burden of physical symptoms and psychological discomfort , end stage renal disease patients with Hemodialysis Maintainence along diabetic nephropathy have a lower health related quality of life and may have state of depression which also leads to poor physical function. Importance for exercise therapy is highlighted in guidelines of National Kindey foundation to increase physical activity in patients .There are two ways that exercise training can be administered: as an intradialytic (during dialysis) or extra dialytic (after dialysis). Studies have indicated that while extra dialytic exercise may yield greater advantages in terms of functional ability and exercise capacity, compliance with extra dialytic therapies is lower. The American College of Sports Medicine (ACSM) guidelines for an exercise prescription state that people with hemodialysis (HD) should exercise three to five days a week

So the need of this study is to determine how the patients responded to the exercises and how they improved in terms of activities of daily living as well as mental health and quality of life

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
35.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Patients, both male and female, 35 to 50 years of age
  • The population that speaks Kannada and English
  • Diabetic nephropathy and type 2 diabetes are present in the patients.
  • 4.Less than 13 mL·h−1·kg−1 is the targeted ultrafiltration rate.
  • BMI (body mass index) more than 26.

排除标准

  • 1.Erratic vital signs
  • Individuals with symptoms or recent hospitalizations
  • Missed prior HD session 4.Ineffective central venous catheter or arteriovenous fistula.

结局指标

主要结局

Physical Function Test with 6 minute walk test, 30 seconds sit to stand test, Hand grip strength of non cannulated arm using dynamometer and Lower limb strength using dynamometer will be assessed.

时间窗: Pre-Intervention (1st Day) and Post intervention and intervention period is 3 times for 8 weeks

Hospital Anxiety and Depression scale (HADS) for assessing depression in patients with Diabetic Nephropathy.

时间窗: Pre-Intervention (1st Day) and Post intervention and intervention period is 3 times for 8 weeks

Kidney Disease Quality of life (KDQoL) questionnaire for assessing health related quality of life in Diabetic nephropathy patients

时间窗: Pre-Intervention (1st Day) and Post intervention and intervention period is 3 times for 8 weeks

次要结局

  • Not Applicable(Not Applicable)

研究者

申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Shetty Kashish Prabhakar

Nitte Institute of Physiotherapy, Nitte Deemed to be university

研究点 (1)

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