Effects of a Whole Body Vibration Training on the Exercise Performance in Patients After Lung Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 140
- 试验地点
- 2
- 主要终点
- change in 6-minute walking distance
研究概览
简要总结
Pulmonary rehabilitation has been established as an evidence-based and recommended therapy in patients following lung transplantation. Exercise training has been shown to be a cornerstone of an inpatient rehabilitation program to reduce muscle dysfunction and improve exercise performance. In our study we will investigate the benefit of a whole body vibration training in addition to a standard pulmonary rehabilitation program that includes endurance and strength training. We will include a total of 140 patients (70 patients < 1 year after lung Transplantation and 70 patients > 1 year after lung Transplantation). Our hypothesis is that an addtitional whole body vibration training produces a greater benefit to exercise capacity in lung transplantat patients (LTx).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •participation in an inpatient rehabilitation program
- •double or single lung transplantation due to chronic obstructive pulmonary disease, Alpha-1-antitrypsine deficiency, interstitial lung disease
排除标准
- •severe exacerbation in the last 4 weeks with the necessity of delivering antibiotics/ corticosteroids
- •non-compliance
结局指标
主要结局
change in 6-minute walking distance
时间窗: change from baseline to day 21
次要结局
- change in Fmax(change from baseline to day 21)
- change in fibre cross sectional area(change from baseline to day 21)
- change in body cell mass(change from baseline to day 21)
- change in Wmax(change from baseline to day 21)
- change in quality of life(change from baseline to day 21)
- change in IGF-1(change from baseline to day 21)
- change in chair rise time(change from baseline to day 21)
研究者
Klaus Kenn
Dr. med. Klaus Kenn, Head physician
Schön Klinik Berchtesgadener Land