Comparison of emergence time between sevoflurane alone and short duration desflurane after sevoflurane in general anesthesia patients

Kosin University Gospel Hospital0 个研究点目标入组 70 人开始时间: 待定最近更新: 2022年2月7日

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•1) Patients aged 18-65 years
•2) Patients expected to undergo general anesthesia for more than 2 hours during elective surgery
•3) Patients corresponding to American Society of Anesthesiologist Status 1-2
•? American Society of Anesthesiologist Status 1: Normal healthy patient
•? American Society of Anesthesiology Classification 2: Patients with mild systemic disease (mild systemic disease without functional impairment)

•1) Patients under total intravenous anesthesia
•2) Emergency surgery patients
•2) body mass index = 30 kg/m2
•3) Pregnant and lactating women
•4) Patients with lung diseases such as asthma and COPD
•5) Patients allergic to drugs (including inhaled anesthetics)
•a. Patients with a history of hypersensitivity to sevoflurane, desflurane, or other halogenated anesthetics
•b. Patients with a history of hypersensitivity to remifentanil and other fentanyl analogues
•c. Patients with a history of hypersensitivity to rocuronium and any of its components or neuromuscular blockers
•6) Patients with kidney disease (patients with creatinine clearance less than 60ml/min, patients with renal impairment with a baseline blood creatinine value of 1.5 mg/dL or more)
•7) Patients with liver dysfunction
•8) Patients with neuromuscular junction disease, including patients with myasthenia gravis and myasthenia gravis
•10) Patients who have difficulty in voluntary consent;
•11) Patients with a history of psychiatric disorders, including those with difficulty in normal communication
•12) Past and family history of malignant hyperthermia
•13) Patients with convulsions and patients with acute hepatic porphyria

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