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临床试验/CTRI/2025/11/096802
CTRI/2025/11/096802尚未招募2/3 期

Comparative Evaluation of Efficacy of Bhukharjaadi (Lepidagathiscristata Wild.) Gargles vs. Jati (Jasminumgrandiflorum Linn.) Gargles in the Management of Pittaj Mukhapak (Aphthous ulcer.)-Randomized Controlled Trial

MGACHRC1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2026年1月1日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
reduction of pain redness lesion and infection caused by aphthous stomatitis

研究概览

简要总结

Introduction : In Ayurveda, Mukhapak is a considered as a specific disease with its own specific Nidana, Purvarupa,Rupa, Samporapatiand Chikitsa which is correleated with Apthous stomatits in modern science,Modern treatment of mouth ulcer has lots of side effects, such as tooth and tongue staining, taste alteration, mouth irritation, so it is need to find alternative, safe and cost-effective herbal drug. epidagathis cristata is a traditionally used as treatment of mouth ulcer in various parts of Madhya Pradesh, Tamil Nadu, Melghat, M.S&dist. of Gadchiroli in Maharashtra.Jaati is also used traditionally in treatment of mukhapak(aphthous stomatitis).Gargles of above mentioned drug will be used in randamoized,single-blind,controlled trial,there is no clinical trial done on lipadihathis cristata therfore,pilot study of dosage will be conducted on  15 patients. Total 50 patient will be taken for study.The study aims to validate and compare there effectiveness,provide evidence based,affordable,and hostalic Ayurvedic options for aphthous stomatitis

研究设计

研究类型
Interventional
分配方式
Na
盲法
Participant Blinded

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • Patient having recurrent episodes of mukhapak Patient having intolerance to eat spicy food.
  • patient having change in color of oral mucosa Patient having history of burning sensation in oral cavity.

排除标准

  • Known case of oral submucosal fibrosis.
  • Known case of gastritis.
  • Traumatic ulcers.
  • Oro-dental fistula.
  • Gingivitis.

结局指标

主要结局

reduction of pain redness lesion and infection caused by aphthous stomatitis

时间窗: 7 days

次要结局

  • not avilable

研究者

发起方
MGACHRC
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Sonali Deshpande

Mahatma Gandhi Ayurved college Hospital and Research

研究点 (1)

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