NCT03091166已完成4 期
The Effect of Prophylactic Dexmedetomidine Administration on the Outcome in Patients Undergoing Surgery With Cardiopulmonary Bypass
Moscow Regional Research and Clinical Institute (MONIKI)1 个研究点 分布在 1 个国家目标入组 169 人开始时间: 2016年12月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 169
- 试验地点
- 1
- 主要终点
- 30DM
研究概览
简要总结
Investigation of effect of perioperative Dexmedetomedine administration on mortality, length of ICU and hospital stay, delirium onset, major adverse cardiac and cerebrovascular events, acute kidney injury in cardiac surgery patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed agreement
- •Elective surgery
- •Use of CPB
排除标准
- •Previous prolonged immobilization
- •Reoperation
研究组 & 干预措施
Dexmedetomidine
Active Comparator
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
30DM
时间窗: 30 days after surgery
30-day mortality
Delirium
时间窗: 30 days after surgery
Postoperative delirium
次要结局
- VIS(5 days after surgery)
- AKI(7 days after surgery)
- Subsyndromal delirium(30 days after surgery)
- ICU-LOS(7 days after surgery)
- H-LOS(30 days after surgery)
- MACCE(30 days after surgery)
研究者
Oleg A. Grebenchikov
senior researcher
Moscow Regional Research and Clinical Institute (MONIKI)
研究点 (1)
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