跳至主要内容
临床试验/CTRI/2024/11/076888
CTRI/2024/11/076888尚未招募不适用

A microbiological evaluation of disinfection of the root canal system using sodium hypochlorite and its combination as irrigants -an in vivo study

Dasmesh institute of research and dental sciences1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年12月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
to evaluate the antibacterial effectiveness of sodium hypochlorite and its different combination when used as irrigating solutions in non-vital single rooted tooth by counting the bacterial colony count.

研究概览

简要总结

For endodontic study chemicomechanical preparation is must. The purpose of this in-vivo study will be to compare the antimicrobial properties of four different irrigating solutions.100 sample will be randomly collected and divided into four groups. The initial root canal sample will be obtained post accessing the canal and confirming its patency. Subsequently, the second sample will be collected following biomechanical preparation utilizing one of the irrigants. The root canal samples will be analyzed microbiologically, followed by a comparative assessment of the antimicrobial effectiveness root canal irrigants using statistical methods

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
15.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patient age should be between 15-60 years with no medical history and teeth with necrotic pulp of either carious or non-carious origin and with closed apex.

排除标准

  • immunocompromised patient , patient with open apex, internal and external resorption, and patients who are allergic.

结局指标

主要结局

to evaluate the antibacterial effectiveness of sodium hypochlorite and its different combination when used as irrigating solutions in non-vital single rooted tooth by counting the bacterial colony count.

时间窗: the microbial sample will be taken on the first treatment appointment of the patient after the access opening is done in the tooth and after the biomechanical preparation and irrigation of the tooth. | the sample will be taken using sterile paper point and will be stored in thiogycolate solution and will be allowed to grow for 24 hours. then microbial colony count will be done to check for the antimicrobial efficacy of the each irrigant.

次要结局

未报告次要终点

研究者

发起方
Dasmesh institute of research and dental sciences
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Tarun kumar

Dasmesh institute of research and dental sciences

研究点 (1)

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