Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change in Scar
研究概览
简要总结
Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 12 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 12 to 60 years
- •Atrophic scars (traumatic or surgical)
- •Completely healed scars
排除标准
- •Patients with a tendency or history of hypertrophic or keloidal scars
- •Patients who received treatment for their scar in the past 3 months
- •Diabetic patients or those with a history of Dysglycemia
- •Pregnant, or lactating females
- •Patients with active infection at the site of scar
- •Patients currently receiving isotretinoin treatment or in the past month
结局指标
主要结局
Change in Scar
时间窗: 4 months
According the different scar assessment scores (e.g.POSAS score - The Patient and Observer Scar Assessment Scale score, range from 6 to 60, the higher the score the worse the scar, lowering in the score denotes improvement )
次要结局
未报告次要终点
研究者
Dalia Ibrahim Halwag
Lecturer and Consultant of Dermatology, Venereology and Andrology, Faculty of Medicine
Alexandria University