Impact of Augmenting Exercise Intensity vs. Frequency on Peak Work Rate
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Peak work rate
研究概览
简要总结
The purpose of this study is to compare the impact of augmenting exercise intensity and augmenting exercise frequency on peak work rate. Participants will complete exercise tests and provide 8 skeletal muscle samples following a within-subjects randomized crossover design utilizing single-leg cycling. Both training periods will be 4 weeks long and skeletal muscle biopsies will be collected from both legs before and after each training period. All exercise sessions will be supervised, take place in the investigator's laboratory, and occur on stationary bikes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Recreational active (<3 hours per week of aerobic exercise)
- •Willing to provide skeletal muscle biopsies
排除标准
- •Cardiovascular or metabolic disease
- •Athletes or individuals exceeding 3 hours per week of aerobic exercise
研究组 & 干预措施
Intensity then Frequency
Training period 1: Intensity comparison Training period 2: Frequency comparison
干预措施: Intensity comparison (Behavioral)
Frequency then Intensity
Training period 1: Frequency comparison Training period 2: Intensity comparison
干预措施: Frequency comparison (Behavioral)
Frequency then Intensity
Training period 1: Frequency comparison Training period 2: Intensity comparison
干预措施: Intensity comparison (Behavioral)
Intensity then Frequency
Training period 1: Intensity comparison Training period 2: Frequency comparison
干预措施: Frequency comparison (Behavioral)
结局指标
主要结局
Peak work rate
时间窗: Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart)
Change in Highest work rate achieved (30s period) during incremental exercise tests
次要结局
- Peak oxygen uptake(Before exercise training on two days (~7 and 6 days before first training session; ~24 hours apart), and after exercise on two days (~48-96 hours after the last training session; ~24 hours apart))
- Maximal citrate synthase activity(Before exercise training (~7 days before first training session), and after exercise training (~48-72 hours after the last training session))
研究者
Brendon Gurd, PhD
Professor, School of Kinesiology & Health Studies, Queen's University
Queen's University