NCT06129799招募中不适用
Exercise CMR in (Paradoxical) Low-flow Low-gradient Aortic Stenosis
University of Göttingen1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2023年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Composite of events: number of participants with cardiovascular death or heart failure hospitalisation
研究概览
简要总结
Patient with paradoxical or conventional low-flow low-gradient aortic stenosis on echocardiographic assessment will undergo physiological exercise-stress CMR in addition to guideline recommended surveys prior to TAVR.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •paradoxical or conventional severe low-flow low-gradient aortic stenosis
排除标准
- •CMR incapable device
- •unable to undergo 40 min scan (can not lie flat, claustrophobia)
- •renal insufficiency (eGFR <30 ml/min/1.73m²)
- •allergy against contrast agent
- •unable to exercise in supine position
结局指标
主要结局
Composite of events: number of participants with cardiovascular death or heart failure hospitalisation
时间窗: 12 months
次要结局
未报告次要终点
研究者
Sören Backhaus
Principal Investigator
University of Göttingen
研究点 (1)
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