EUCTR2016-002015-17-DK进行中（未招募）1 期
ow-flow Low-gradient Aortic Stenosis – Diagnostic Usefullness of Ivabradine
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •Inclusion criteria
- •1.Low-flow (SV index<35 ml/m2) low-gradient (meangradient <40 mmHg) AS with AVA<1,0 cm2
- •2.Age > 18 years
- •3.Signed informed consent
- •4.Heart rate > 60 beats per minute
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 10
排除标准
- •1.Other moderate-severe valvular heart disease other than AS
- •2.Unwilling to participate in the study
- •3.Mental disorder precluding informed consent
- •4.Poor echocardiographic window
- •5.Chronic atrial fibrillation
- •6.Sinus node dysfunction
- •7.Bradycardia < 60 BPM
- •8.Complete AV block or permanent cardiac pacemaker
- •9.Hypotension <90/50 mmHg
- •10.Concomitant treatment with diltiazem or verapamil
- •11.Liver dysfunction with ALAT twice upper limit of normal.
- •12. Pregnancy
研究者
相似试验
招募中
不适用
Silent and Apparent Neurological Injury in Transcatheter Aortic Valve Implantation (TAVI)Transcatheter Aortic Valve Implantation (TAVI)Neurological InjuryCardiovascular - Other cardiovascular diseasesSurgery - Other surgeryStroke - IschaemicACTRN12613000083796Critical Care Research Group (CCRG)80
Unknown
不适用
Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)Aortic Valve StenosisNCT01835028Laval University320
招募中
不适用
WItten heaRt failurE in Aortic Stenosis study - Prospective diagnostic study to investigate the hemodynamic basis of an irreversible left ventricular failure in severe aortic stenosisI35.0I42.8Aortic (valve) stenosisOther cardiomyopathiesDRKS00009993Kardiogische Klinik, Marien-Hospital Witten, Ruhr-Universität Bochum40
已完成
不适用
Aortic Stenosis * Identification of high-risk valve pathology using STRESS physiology (AoS-STRESS)aortic valve stenosisnarrowed heart valve10046973NL-OMON43812Catharina-ziekenhuis50
招募中
不适用
Exercise CMR in (p)LF-LG ASAortic Stenosis, SevereNCT06129799University of Göttingen100