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临床试验/NCT05172661
NCT05172661已完成不适用

Effects of Physical-Cognitive Training With Different Task Models on Dual-Task Walking in Parkinson's Disease With Mild Cognitive Impairment

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2021年11月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
27
试验地点
1
主要终点
Change from baseline dual-task walking performance at 8 weeks

研究概览

简要总结

The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
40 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • a diagnosis of idiopathic Parkinson's disease
  • have decreased cognitive functions but do not interfere with functional independence
  • Montreal Cognitive Assessment (MoCA): 21-25
  • able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°

排除标准

  • a diagnosis of dementia
  • other diseases that may influence cognitive functions or walking performance
  • a history of brain surgery
  • modification of the medication during the exercise intervention

结局指标

主要结局

Change from baseline dual-task walking performance at 8 weeks

时间窗: 8 weeks

Change from baseline Montreal Cognitive Assessment (MoCA) score at 8 weeks

时间窗: 8 weeks

MoCA: 0-30 points, higher scores mean a better outcome

Fall frequency

时间窗: 20 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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