Metabolic Effects of Snuff and Red Wine
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- level of metabolic rate
研究概览
简要总结
About 14 healthy participants, consume a standardized breakfast combined with either using regular or nicotine-free moist snuff. The metabolic rate is measured every hour for four hours on each occasion starting in the morning. Participants are also randomized to get red wine or non-alcoholic red wine to the meal.
详细描述
About 14 healthy participants, consume a standardized breakfast combined with either using regular or nicotine-free moist snuff. The metabolic rate is measured measured before the meal and then every hour for a total of four hours on each occasion that starts in the morning. Participants are also randomized to get red wine or non-alcoholic red wine to the meal. Since there are four possible combinations of the wine and the snuff, all participants do the test on four occasions. Except for metabolic rate we will also analyze hormone responses regarding appetite or hunger.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
We use non-alcoholic or alcohol containing wine and regular or nicotine free snuff
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •No significant disease -
排除标准
- •known illnesses, thyroid disease, need to take prednisolone, psychiatric disease,inability to understand Swedish
研究组 & 干预措施
red wine and snuff
regular red wine and moist snuff
干预措施: Wine with or without alcohol and snuff with or without nicotine (Other)
red wine and nicotine-free snuff
regular red wine and nicotine-free snuff
干预措施: Wine with or without alcohol and snuff with or without nicotine (Other)
non alcoholic red wine and regular moist snuff
non alcoholic red wine and regular moist snuff with nicotine
干预措施: Wine with or without alcohol and snuff with or without nicotine (Other)
non-alcoholic red wine and nicotine-free snuff
Non-alcoholic red wine and nicotine-free snuff
干预措施: Wine with or without alcohol and snuff with or without nicotine (Other)
结局指标
主要结局
level of metabolic rate
时间窗: 4 hours
Measurement of metabolic rate by registration of CO2 in breath and the oxygen uptake
次要结局
- sense of appetite(4 hours)
研究者
Fredrik H Nystrom
professor, MD
University Hospital, Linkoeping