NCT05015231招募中不适用
Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients: a Pilot Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Assessment of changes in renal hemodynamics by multiparametric MRI after closure of AVF access
研究概览
简要总结
Assessment of changes of renal hemodynamics by multiparametric MRI after closure of AVF access.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed consent
- •Age > 18 years
- •Patients wishing to close the fistula and planned for surgical fistula closure
- •eGFR CKD EPI ≥ 45 ml/min/1.73m2 at one year post transplantation
- •Stable eGFR within the past 6 months
- •Controlled blood pressure
排除标准
- •Kidney Transplantation < 12 months before fistula closure
- •Proteinuria > 500mg/d
- •Presence of donor specific antibodies
- •Rejection within the past 6 months
- •BK virus replication within the past 3 months
- •Cardiac pacemaker, which is not compatible with MRI
- •Claustrophobia
结局指标
主要结局
Assessment of changes in renal hemodynamics by multiparametric MRI after closure of AVF access
时间窗: evaluation of short term changes within 2 weeks after fistula closure and longterm changes 6 months after fistula closure
Assessing changes in renal oxygenation
次要结局
- Correlation between AVF access flow and changes as assessed during pneumatic fistula compression with changes in renal hemodynamics after fistula closure(evaluation of short term changes within 2 weeks after fistula closure and longterm changes 6 months after fistula closure)
研究者
研究点 (1)
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