Supernormal Oxygen Delivery for Patients With Severe Burns：A Randomized Controlled Trial
试验速览
- 阶段
- 早期 1 期
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Complication
研究概览
简要总结
This is a randomized double-blinded study to investigate in which the groups are designated as the control group and the goal-directed fluid therapy group to further evaluate significant differences in rate of complications during burn surgery.
详细描述
This is a randomized double-blinded study to investigate the effect of control group and the goal-directed fluid therapy group on complications during surgery of the burn patients. The groups are designated as the control group and the oal-directed fluid therapy group to further evaluate significant differences in complications during the surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Severe burn patients
排除标准
- •Patients or families refuse to sign consent
研究组 & 干预措施
Goal-directed fluid group
Intervention: administration of dobutamine 0.01 - 0.04 U/min after induction of anesthesia.
Intraoperative fluid management: administration of 2-4 ml/kg/hr of crystalloid solution.
干预措施: Dobutamine (Drug)
结局指标
主要结局
Complication
时间窗: One week after operation
perioperative complications
次要结局
未报告次要终点
研究者
Liang Bing
Associate senior doctor
Guangzhou Red Cross Hospital