NCT00539786Unknown不适用
Clinical Usefulness of Proton Pump Inhibitor Test for Identifying Gastroesophageal Reflux Disease in Patients With Extraesophageal Symptoms
适应症
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Symptom responders after PPI trials
研究概览
简要总结
PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD. However, this diagnostic strategy has not been well established in patients with extraesophageal manifestation of GERD. In this study, we aim to see the relevance of PPI test in diagnosing GERD in patients with extraesophageal symptoms.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with extraesophageal manifestation symptoms of GERD
排除标准
- •laryngeal, pharyngeal, liver, lung, renal, or hematological disorders
- •a history of gastrointestinal surgery, and a history of connective tissue disorders.
- •patients with duodenal or gastric ulcers as well as other significant lesions, such as gastric cancer, esophageal cancer, or subepithelial tumors more than 1 cm observed on the upper endoscopy
结局指标
主要结局
Symptom responders after PPI trials
时间窗: 2 weeks after PPI trials
次要结局
未报告次要终点
研究者
Poong-Lyul Rhee
Professor
Samsung Medical Center
研究点 (2)
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