Glucose Response From Antioxidant Rich Potato Chips
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 主要终点
- Blood Glucose
研究概览
简要总结
Assess impact of potato phytochemical on post-prandial gastric emptying and glucose release from products in a pilot human study.
详细描述
Preclinical data obtained using an Caco-2 intestinal cell model and enzyme assays suggest phenolic-rich potato extracts decrease intestinal glucose transport. The aim is to determine if these effects extend to the the an in vivo situation. Specifically, the glycemic response following consumption of phenolic rich pigmented potatoes compared to white potatoes with lower phenolic content will be measured. Gastric emptying will also be measured to show the effects are in fact due to rate of carbohydrate digestion and intestinal glucose transport and not gastric emptying rate.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI 18-25 non-smoker
排除标准
- •BMI outside 18-25 smoker previous gastrointestinal disease or other disease
结局指标
主要结局
Blood Glucose
时间窗: up to 2 hours
blood taken at 10, 20, 30, 60, and 120 minutes by finger prick
Gastric emptying
时间窗: up to 4 hours
Breath Hydrogen concentrations will be measured every 15 minutes for 4 hours
次要结局
未报告次要终点
研究者
Richard Mattes
Prof. Nutrition Sciences
Purdue University