Impact of Catheter Ablation of Ventricular Arrhythmias on Suboptimal Biventricular Pacing in Cardiac Resynchronization Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Percentage of Biventricular pacing
研究概览
简要总结
Cardiac resynchronization therapy reduces mortality in patients with systolic heart failure and left bundle branch block. Reduced biventricular pacing can lead to therapy failure. Most effective mortality reduction was seen with a BiV pacing above 98%.
Reduced BiV pacing is a common phenomenon with potential impact on CRT-response and pts' prognosis. Frequent ventricular ectopy may be associated with attenuated benefit from CRT. The investigators sought to systematically assess the effect of ventricular arrhythmia treatment on BiV pacing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •reduced biventricular pacing <98% due to ventricular arrhythmia
排除标准
- •reduced biventricular pacing <98% due to other cause
- •pregnancy
研究组 & 干预措施
Catheter ablation group
Patients with reduced biventricular pacing due to PVC or VT receiving catheter ablation of PVC/VT according to guidelines and clinical practices
干预措施: Catheter ablation of ventricular arrhythmia (Procedure)
Medical treatment group
Patients with reduced biventricular pacing due to PVC or VT receiving intensified medical therapy (antiarrhythmics/betablocker) according to guidelines and clinical practices
干预措施: Intensified medical therapy (Drug)
结局指标
主要结局
Percentage of Biventricular pacing
时间窗: 3 month after intervention biventricular pacing (%) is routinely monitored
Influence of intervention (Ablation/medical treatment) on previously reduced biventricular pacing percentage (\<98%). Biventricular pacing is measured in percentage of stimulation and is monitored at routine device interrogation.
次要结局
未报告次要终点