Effects of Exercise Training on Markers of Lung Inflammation and Clinical Crontrol in Asthma Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Exhaled Nitric Oxide (FeNO) Level
研究概览
简要总结
The purpose of this study is to assess the effects of a physical training program with active video game in inflammatory markers, quality of life variables , clinical control and physical and functional respiratory assessment of asthmatic children from 5 to 11 years.
详细描述
The aim of the present study will be to determine whether an aerobic exercise using an active video game system improves asthma control, lung inflammation and functional capacity in children with moderate or severe asthma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 5 Years 至 11 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages 5 to 11 years;
- •Having a diagnosis of asthma, according to the criteria of the National Heart, Lung, and Blood Institute, and
- •Not be included in any program of regular physical activity.
排除标准
- •Having received aminophylline and theophylline or oral corticosteroids in the last 30 days;
- •Respiratory infection have shown over the past two months;
- •Have done with inhaled bronchodilator in less than 12 hours before the assessment;
- •Inability to perform any of the tests;
- •Have heart disease of inflammatory origin, congenital or ischemic;
- •Being in the presence of any infectious process with fever and
- •Do not agree to the terms of consent
研究组 & 干预措施
Aerobic exercise
The aerobic training will be done on the treadmill with heart monitors with intensity required to achieve 70% of maximum heart rate reached the maximum test for thirty minutes.
干预措施: Aerobic exercise group (Other)
Video game
The training with video game will be done with heart rate monitors with intensity required to achieve 70% of maximum heart rate reached the maximum test for thirty minutes.Will be used Kinect games ( reflex ridge- Adventure).
干预措施: Video game group (Other)
结局指标
主要结局
Exhaled Nitric Oxide (FeNO) Level
时间窗: The FeNO level was performed in week 8
The measurement of exhaled FeNO level is performed by several commercially available devices, however the equipment NIOX ® (Aerocrine, Sweden) analyzer is the only FDA-approved and Anvisa (Food and Drug Administration) for clinical monitoring of asthma. The measure will be performed before and after the training program of exercise, or pulmonary rehabilitation, by means of portable equipment NIOX MINO ®.
次要结局
- Treadmil Test (Bruce Protocol)(8 week distance walked on treadmill test)
- Body Composition(baseline and after 8 weeks)
- Pulmonary Function(baseline and after 8 weeks)
研究者
Evelim Leal de Freitas Dantas Gomes, PhD
PhD in science Rehabilitation
Hospital Sirio-Libanes