A Ranadomized controlled trial to evaluate an add on effect of kantakari Vati with ARBs with or without diuretic in managemant of Essential Hypertension
试验速览
- 阶段
- 2/3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- To evaluate the add on effect of Kantakari Vati with ARBs with or without diuretic
研究概览
简要总结
Patient between 20 to 60 years of age taking ARBs with or without diuretic antihypertensive but still having systolic blood pressure of ≥ 130 mmHg and/or diastolic blood pressure of ≥80 mmHg with or without symptoms Shirshoola (Headache), Hridspandana (Palpitations), Bhrama (Giddiness), Klama (Fatigue) will be included in this study and will be treated with kantakari vati.
- INCLUSION CRIETERIA:
- Patients having Stage I hypertension, isolated systolic and isolated diastolic hypertension. 2.Age of the patient between 20 to 60 years.
- Shirashool, Klama, Hridspandana, Bhrama patient having these symptoms of Hypertension will be included in the clinical study.
- Patients taking Angiotensin Receptor Blockers with or without diuretic and still having raised blood pressure. 6.Diabetic patients with ongoing allopathy medications only. 7.Patient on previous ayurvedic medications, 7 days washout period will be given to avoid drug interaction.
- Patients having serum creatinine level less than 1.4 mg/dl.
- EXCLUSION CRITERIA:
- Patients having Stage II, hypertensive crisis will be excluded.
- Patient suffering from any other serious systemic illness like Acute cerebrovascular diseases, Acute coronary syndrome, Acute Haemorrhagic conditions, Acute septic shock etc. 3.Secondary Hypertension or Accelerated Hypertension.
- Pregnant women and lactating mothers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients having Stage I hypertension, isolated systolic and isolated diastolic hypertension.
- •2.Age of the patient between 20 to 60 years.
- •Shirashool, Klama, Hridspandana, Bhrama patient having these symptoms of Hypertension will be included in the clinical study.
- •Patients taking Angiotensin Receptor Blockers with or without diuretic and still having raised blood pressure.
- •6.Diabetic patients with ongoing allopathy medications only.
- •7.Patient on previous ayurvedic medications, 7 days washout period will be given to avoid drug interaction.
- •Patients having serum creatinine level less than 1.4 mg/dl.
排除标准
- •1.Patients having Stage II, hypertensive crisis will be excluded.
- •2.Patient suffering from any other serious systemic illness like Acute cerebrovascular diseases, Acute coronary syndrome, Acute Haemorrhagic conditions, Acute septic shock etc.
- •3.Secondary Hypertension or Accelerated Hypertension.
- •Pregnant women and lactating mothers.
结局指标
主要结局
To evaluate the add on effect of Kantakari Vati with ARBs with or without diuretic
时间窗: inclusion day,15th day,30th day
in Vyanodan kala in decreasing the sign and symptoms of essential hypertension in
时间窗: inclusion day,15th day,30th day
duration of 30 days.
时间窗: inclusion day,15th day,30th day
次要结局
- 1. To study the Ayurveda concepts of Hypertension.(2. To see add on effect of Kantakari Vati in Essential Hypertension.)
研究者
Dr Vijayalaxmi Sujay Patil
MAMs Sumatibhai Shah Ayurved Mahavidyalaya Hadapsar
