跳至主要内容
临床试验/CTRI/2025/01/079564
CTRI/2025/01/079564招募中2/3 期

A Ranadomized controlled trial to evaluate an add on effect of kantakari Vati with ARBs with or without diuretic in managemant of Essential Hypertension

Dr Priya Pravin Shevale1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2025年2月8日最近更新:

试验速览

阶段
2/3 期
状态
招募中
发起方
入组人数
66
试验地点
1
主要终点
To evaluate the add on effect of Kantakari Vati with ARBs with or without diuretic

研究概览

简要总结

Patient between 20 to 60 years of age taking ARBs with or without diuretic antihypertensive but still having systolic blood pressure of ≥ 130 mmHg and/or diastolic blood pressure of ≥80 mmHg with or without symptoms Shirshoola (Headache), Hridspandana (Palpitations), Bhrama (Giddiness), Klama (Fatigue) will be included in this study and will be treated with kantakari vati.

  1. INCLUSION CRIETERIA:
  1. Patients having Stage I hypertension, isolated systolic and isolated diastolic hypertension. 2.Age of the patient between 20 to 60 years.
  2. Shirashool, Klama, Hridspandana, Bhrama patient having these symptoms of Hypertension will be included in the clinical study.
  3. Patients taking Angiotensin Receptor Blockers with or without diuretic and still having raised blood pressure. 6.Diabetic patients with ongoing allopathy medications only. 7.Patient on previous ayurvedic medications, 7 days washout period will be given to avoid drug interaction.
  4. Patients having serum creatinine level less than 1.4 mg/dl.
  1. EXCLUSION CRITERIA:
  1. Patients having Stage II, hypertensive crisis will be excluded.
  2. Patient suffering from any other serious systemic illness like Acute cerebrovascular diseases, Acute coronary syndrome, Acute Haemorrhagic conditions, Acute septic shock etc. 3.Secondary Hypertension or Accelerated Hypertension.
  3. Pregnant women and lactating mothers.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients having Stage I hypertension, isolated systolic and isolated diastolic hypertension.
  • 2.Age of the patient between 20 to 60 years.
  • Shirashool, Klama, Hridspandana, Bhrama patient having these symptoms of Hypertension will be included in the clinical study.
  • Patients taking Angiotensin Receptor Blockers with or without diuretic and still having raised blood pressure.
  • 6.Diabetic patients with ongoing allopathy medications only.
  • 7.Patient on previous ayurvedic medications, 7 days washout period will be given to avoid drug interaction.
  • Patients having serum creatinine level less than 1.4 mg/dl.

排除标准

  • 1.Patients having Stage II, hypertensive crisis will be excluded.
  • 2.Patient suffering from any other serious systemic illness like Acute cerebrovascular diseases, Acute coronary syndrome, Acute Haemorrhagic conditions, Acute septic shock etc.
  • 3.Secondary Hypertension or Accelerated Hypertension.
  • Pregnant women and lactating mothers.

结局指标

主要结局

To evaluate the add on effect of Kantakari Vati with ARBs with or without diuretic

时间窗: inclusion day,15th day,30th day

in Vyanodan kala in decreasing the sign and symptoms of essential hypertension in

时间窗: inclusion day,15th day,30th day

duration of 30 days.

时间窗: inclusion day,15th day,30th day

次要结局

  • 1. To study the Ayurveda concepts of Hypertension.(2. To see add on effect of Kantakari Vati in Essential Hypertension.)

研究者

发起方
Dr Priya Pravin Shevale
申办方类型
Other [Self ]
责任方
Principal Investigator
主要研究者

Dr Vijayalaxmi Sujay Patil

MAMs Sumatibhai Shah Ayurved Mahavidyalaya Hadapsar

研究点 (1)

Loading locations...

相似试验