Community based Surveillance to estimate incidence and sero prevalence of acute febrile illness with focus on Dengue and Chikungunya – A prospective multi-centric cohort Study

The proposed study is expected to determine the burden of diseases causing acute febrile illness with focus on Dengue and Chikungunya at community level and monitor to estimate the seasonal variations and rate of transmission in the incidence of disease, Risk factors for infection can be identified which might inform future control strategies. The serial surveys in the same set of individuals will help in measuring the antibody levels over a period of time and understand the proportion of individuals who are able to mount a neutralization response and the duration for which immunity lasts after infection.

The cost per case of Dengue (including Dengue Haemmohagic fever) and Chikungunya fever reported from the established cohort will be calculated by summing the following costs: (1) direct medical costs – costs directly attributable to patient care. It will include costs for hospitalization and cost of an ambulatory visit in public and private settings (including professional services, medical inputs, medical drugs and related products, as well as laboratory tests); (2) direct non-medical costs – costs directly attributable to illness but are not involved in direct purchase of medical services. It will include food, lodging and travel expenses incurred during the period of treatment (3) indirect costs (to the patient and their family) resulting from loss of productivity and loss of earnings. All costs will be calculated in Indian Rupees (INR).