Total Laparoscopic vs Open Pancreaticoduodenectomy for the Treatment of Periampullary Adenocarcinomas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- The incidence of pancreatic fistula after laparoscopic pancreaticoduodenectomy in comparison to open surgery
研究概览
简要总结
Laparoscopic pancreaticoduodenectomy (LPD), a surgical option for nonpancreatic periampullary adenocarcinoma (NPPA), is a complex procedure that has become increasing popular. However, there is no consensus as to whether this technique should be performed routinely. Our aim was to evaluate the outcomes of LPD compared with open pancreaticoduodenectomy (OPD).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Body mass index <28.0 kg/m
- •Ampullary tumors, duodenal tumors restricted to the second part of the duodenum, or lower common bile duct tumors.
- •Carefully confirmed resectability of the tumors based on preoperative radiology conducted by experienced radiologists and surgeons.
排除标准
- •• Patients with >180 degrees superior mesenteric artery encasement
- •Any celiac abutment.
- •Unreconstructable superior mesenteric vein/portal occlusion" Aortic invasion or encasement.
- •A history of previous upper abdominal surgery.
- •Tumors extending to the uncinate.
- •Severe cardiorespiratory comorbidities.
研究组 & 干预措施
conventional open pancreaticoduedectomy
15 patients underwent conventional open pancreaticoduedenctomy
干预措施: Conventional open pancreaticoduedectomy (Procedure)
Total laparoscopic pancreaticoduedectomy
15 patients underwent total laparoscopic pancreaticoduedectomy
干预措施: Total laparoscopic pancreaticoduedectomy (Procedure)
结局指标
主要结局
The incidence of pancreatic fistula after laparoscopic pancreaticoduodenectomy in comparison to open surgery
时间窗: in 2 years between 2023 - 2025
Laparoscopic pancreaticoduodenectomy is a complex procedure that has become increasing popular. However, there is no consensus as to whether this technique should be performed routinely. Our aim was to evaluate the outcomes of Laparoscopic pancreaticoduodenectomy compared with open pancreaticoduodenectomy.
次要结局
未报告次要终点
研究者
Mahmoud Rady
Lecturer of general surgery
Theodor Bilharz Research Institute