CTRI/2022/06/043109尚未招募未知
Assessment of prognostic biomarkers to predict pathological complete response in patients with non-metastatic triple-negative breast cancer using a window of opportunity design
ICMR Adhoc extramural grant0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Newly diagnosed triple-negative breast cancer.
- •Age 18 -65 years.
- •ECOG PS 0/1.
- •Early and locally advanced breast cancer (T2/T3/T4b with or without node positive).
- •Planned for neo-adjuvant chemotherapy with anthracycline and taxanes.
- •Bone marrow function- Hb > 9g%, absolute neutrophil count > 1500/ micL, platelet > 1.5 lakhs/ mic L.
- •Renal function- Serum creatinine < 1.5 mg%.
- •Liver function- Serum bilirubin > 1.5 mg%.
- •Normal cardiac function.Â
排除标准
- •The patient is not willing to the second biopsy
- •Pregnant women
- •Breast feeding mother
- •Prior history of any other malignancy
- •Bilateral breast cancer
- •Patient having active local site infection
- •Previous allergy to chemotherapy drugs paclitaxel and carboplatin
研究者
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