Management of Acute Cardiogenic Shock at the New Brunswick Heart Centre
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,416
- 试验地点
- 1
- 主要终点
- Percentage mortality
研究概览
简要总结
In Atlantic Canada, acute myocardial infarction occurs at a rate of 2.9 % of the population and is the most common cause of cardiogenic shock (CS). In many studies, acute myocardial infarction accounts for up to 80% of the patients with CS. While there are different methods of treating patients with CS, the rate of mortality has not significantly improved over the years and remains as high as 50%. Recent studies have shown that a multi-modal, team-based approach can help improve patient outcomes; however, such a standardized approach is yet to be implemented in the New Brunswick Heart Centre (NBHC).
The study aims to understand the difference in outcomes between two groups of patients treated for CS: SHOCK TEAM versus non-SHOCK TEAM. This is a retrospective study of 168 patients using the data from NBHC registry and patient charts. The study duration is 1 year. The primary outcome is hospital survival. Secondary outcomes include time from diagnosis to invasive monitoring and intervention. All data will be analyzed statistically between the two groups. The end goal of the study is to establish standard guidelines to treat CS patients and improve patient survival.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient admitted to the CCU with a diagnosis of CS (SCAI groups C, D or E) at any point during their CCU care.
排除标准
- •CS patients having SCAI groups A, B (this group was used only for preliminary analysis, hence this is the exclusion criteria for all final analyses).
结局指标
主要结局
Percentage mortality
时间窗: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months
Any in-hospital mortality (within Saint John Regional Hospital, another hospital after transfer)
Discharge disposition
时间窗: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months
Discharge of patients home, transfer to another hospital or to another institution (special care home, extra-mural home)
Percentage of missed opportunities
时间窗: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months
Missed opportunities was defined as patients who suffered significant delays or those who did not receive any intervention
Length of stay (LOS))
时间窗: From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months
LOS was considered only for patients who were discharged directly home from Saint John Regional Hospital
次要结局
- Time from diagnosis of shock to in-hospital processes(From the date of hospital admission at Saint John Regional Hospital to the date of discharge, assessed upto 6 months)
研究者
Dr. Jean-François Légaré
Head of Cardiac Surgery
New Brunswick Heart Centre