Reversal of Roux-en-Y Gastric Bypass: A Swedish National Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 199
- 试验地点
- 1
- 主要终点
- Symptom relief
研究概览
简要总结
Objective:
To investigates incidence, indications, symptom relief, complications, and weight outcomes after Roux-en-Y gastric bypass (RYGB) reversal.
Background:
RYGB is an effective treatment for obesity, but in rare cases may be associated with severe long-term complications requiring RYGB reversal. Evidence on incidence and outcomes is limited.
Methods:
This nationwide, multi-center, retrospective cohort study included all patients undergoing RYGB reversal in Sweden between 2007 and 2023. Data were obtained from the Scandinavian Obesity Surgery Registry (SOReg) and medical records.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (≥ 18years) who underwent reversal of RYGB between 2007 and 2023.
排除标准
- •Emergency reversal due to bowel ischemia
- •Reversal following other bariatric procedures (e.g. gastric banding)
- •Partial/functional reversals (e.g., gastro-gastric fistula or anastomosis between the Roux-limb and gastric remnant, without full reversal of RYGB)
研究组 & 干预措施
Adults (≥ 18years) who underwent reversal of RYGB
Included patients were adults (≥ 18years) who underwent reversal of RYGB between 2007 and 2023. Exclusion criteria included emergency reversal due to bowel ischemia, reversal following other bariatric procedures (e.g. gastric banding), or partial/functional reversals (e.g., gastro-gastric fistula or anastomosis between the Roux-limb and gastric remnant, without full reversal of RYGB)
结局指标
主要结局
Symptom relief
时间窗: Through study completion, an average of 2 years.
Symptom relief was classified as no, partial, or complete improvement. Complete improvement was defined as full resolution of the index symptom (e.g., cessation of hypoglycemia, pain-free status without analgesics). Partial improvement denoted a clinically meaningful reduction in symptom severity or frequency that did not meet criteria for complete resolution. No improvement indicated persistent symptoms.
次要结局
- Indications for surgery(Through study completion, an average of 2 years.)
- Weight outcome after surgery(Through study completion, an average of 2 years.)
- Complications(At 30-day follow-up and one-year follow-up after surgery.)
研究者
Ellen Andersson
Associate professor, senior consultant
Vrinnevi Hospital