Randomised comparative clinical study to evaluate the efficacy of Mustadi Yapana Yoga Basti followed by Ashwattha Ksheerapaka and Bimbi Moola Ksheerapaka orally in Shayyamutra with special reference to Nocturnal Enuresis in children.

Nocturnal Enuresis (NE), or bed-wetting, is a psychosomatic disorder that significantly affects the physical and emotional well-being of children, particularly beyond the age of five. It is prevalent in 10–15% of children aged 5–10 years and about 5% in those aged 10–15 years, with a higher incidence in boys. Children with Nocturnal Enuresis often suffer from low self-esteem, social withdrawal, and academic decline. Though often seen as behavioral,Nocturnal Enuresis is increasingly recognized as a developmental delay in achieving nighttime bladder control. While bladder overactivity is a primary cause, conventional treatments like bed alarms and Desmopressin have limitations in compliance and long-term efficacy. In Ayurveda, Nocturnal Enuresis corresponds to Shayyamutra, understood as Anyonya Avrita Vata and Tamo-Kapha Avarana of Hridaya, manifesting as Apana Avrita Vyana Vayu. Management includes Pakvashaya Shodhana with Yapana Basti and Grahi Chikitsa with Mootrasangrahaneeya Dravyas. Previous studies lack a holistic approach. This study aims to address Shayyamutra comprehensively through Mustadi Yapana Yoga Basti and oral administration of Ashwattha and Bimbi Moola Ksheerapaka, which offer Balya, Brimhana, and Mootrasangrahaneeya effects.