Diagnostic Utility of Exercise Cardiac Magnetic Resonance in the Assessment of Cardiac Dyspnea.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Ejection Fraction
研究概览
简要总结
Researchers are examining the diagnostic utility of an exercise cardiac MRI (eCMR) in the assessment of cardiac dyspnea (shortness of breath).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consecutive patients aged ≥18 years years with suspected cardiac dyspnea who are scheduled to undergo right heart catheterization as dictated by a comprehensive examination and echocardiography will be included for enrollment.
排除标准
- •Age <18 years
- •Pregnancy
- •Mechanical ventilation
- •Acute or chronic renal failure (creatinine clearance <30 ml/min or requiring renal replacement therapy)
- •Inability to perform MRI (i.e. claustrophobia, severe obesity (>150 kg), device incompatible with MRI)
- •Inability to exercise
- •Significant arrhythmia that precludes adequate ECG-gating for the MRI (i.e. atrial fibrillation with highly variable cycle lengths)
- •Prior heart or lung transplantation
- •Left ventricular systolic (ejection fraction <50%) or diastolic failure (based on Framingham criteria for heart failure with preserved ejection fraction)
- •Significant left-sided valvular disease (≥moderate aortic stenosis, mitral stenosis, aortic regurgitation, mitral regurgitation) or prior valve surgery
研究组 & 干预措施
Subjects with unexplained but suspected cardiac dyspnea
Subjects with unexplained but suspected cardiac dyspnea who are being scheduled for right heart catheterization will undergo an exercise cardiac magnetic resonance imaging (eCMR).
干预措施: Exercise cardiac magnetic resonance imaging (Diagnostic Test)
结局指标
主要结局
Ejection Fraction
时间窗: Baseline
Measured using exercise cardiac magnetic resonance imaging (eCMR) reported in percentages
Longitudinal Strain Assessment
时间窗: Baseline
Measured using exercise cardiac magnetic resonance imaging (eCMG) reported in percentages
Stroke Volume
时间窗: Baseline
Measured using exercise cardiac magnetic resonance imaging (eCMG) reported in mL
次要结局
未报告次要终点
研究者
Brian Shapiro
Principal Investigator
Mayo Clinic