CTRI/2021/12/039058尚未招募未知
Aqueous angiography in congenital, high pressure juvenile glaucoma and adult onset glaucomas
ARVO0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •This will be a pilot study to analyze the aqueous angiographic signals from representative groups of Congenital glaucoma, Juvenile open angle glaucoma and Primary open angle glaucoma patients who will be posted for cataract or trabeculectomy surgery in the routine Operation theatre.
- •Cases: 10 cases each ofCongenital glaucoma, Juvenile open angle glaucoma, Primary open angle glaucoma patientsand controls who will be already posted in the OT for either cataract surgery or filtering glaucoma surgery.
- •The diagnostic criteria for each of the condition will be defined as below:
- •Congenital glaucoma
- •Inclusion criteria for congenital glaucoma will be as follows: untreated/unoperatedcases of congenital glaucoma with enlarged corneal diameters ( >12 mm) who are diagnosed with baseline IOP records of >22 mm Hg detected before 3 years of age and are scheduled for IOP lowering surgery under general anaesthesia.
- •Adult-Onset POAG
- •These will be unrelated POAG patients diagnosed after the age of 40 years presenting with high baseline IOP >25mmHg, scheduled for IOP lowering/ cataract surgery would be included. Only those eyes that had not undergone previous surgery would be included. They will be diagnosed based on open angle on gonioscopy in both eyes, and glaucomatous optic neuropathy
- •in one or both eyes with visual field loss consistent with optic nerve damage.
- •JOAG Patients
- •These will be unrelated POAG patients diagnosed between 10 and 40 years of age presenting with high baseline IOP >25mmHg, scheduled for IOP lowering/ cataract surgery would be included. Only those eyes that had not undergone previous surgery would be included.
排除标准
- •Patients excluded from the study: those with a history of steroid use, presence of any other retinal or neurologic pathology, evidence of secondary causes of raised IOP such as pigment dispersion, pseudoexfoliation, or trauma, those with any pathology detected on gonioscopy such as angle recession, pigmentation of the angle greater than grade 3, irido-trabecular contact or peripheral anterior synechiae, and patients with nystagmus will be excluded.
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