Glycemic Control Following Occupational Work in a Hot Environment
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 主要终点
- Plasma glucose
研究概览
简要总结
Occupational workers regularly perform physically demanding tasks in hot environments, exposing them to heat stress and potential dehydration. While the physiological impacts of heat exposure are well-documented, its effects on glycemic control remain less understood. Given the rising global temperatures due to climate change and the increasing prevalence of metabolic disorders such as obesity and type 2 diabetes, it is essential to investigate how heat exposure during work influences glycemic regulation. Understanding these interactions will help inform future occupational health guidelines and metabolic health recommendations in physically demanding industries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female
- •Generally fit and healthy
- •Participate in endurance or intermittent exercise at least 3 times a week or minimum of 150 minutes moderate intensity activity per week
排除标准
- •Under 18 or 45 and over,
- •any morbidity or medication that might influence carbohydrate/fat metabolism (i.e., liver/renal/cardiovascular disease) or cycling ability (musculoskeletal injury etc),
- •coagulation or bleeding disorders,
- •blood-borne illness,
- •heart conditions,
- •congenital heart disease,
- •uncontrolled exercise-induced asthma,
- •smoking (including vaping),
- •allergies to the products used in the study,
- •dieting or restrained eating behaviours.
- •Females with amenorrhea would be an exclusion criteria.
结局指标
主要结局
Plasma glucose
时间窗: 8hours
Measured using colorimetric assay from venous blood samples
次要结局
- Plasma insulin(8hours)
- Plasma osmolality(8hours)
- Plasma volume change(8hours)
- Urine volume(8hours)
- Respiratory gas exchanges(8hours)
- Body mass(8hours)
- Urine specific gravity/osmolality(8hours)
- Rectal temperature(8hours)
- Blood pressure(8hours)
- Rate of perceived exertion(8hours)
- Rate of thermal sensation(8hours)
- Feelings of thirst, urge to urinate, GI comfort, and stomach bloatedness(8hours)
研究者
Stephen Mears
Dr - Senior lecturer
Loughborough University