Swiss Primary Sclerosing Cholangitis Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 21
- 主要终点
- Transplantation-free survival rate
研究概览
简要总结
Research project in which biological material is sampled and health-related personal data is further used and collected.
Coded data are used.
详细描述
The investigators wish to collect high quality prospective data on a rare disease in order to elucidate epidemiology, natural history, response to treatment and outcome. In addition, a biobank allows addressing specific scientific issues on a variety of open questions. The cohort will provide a platform for carrying out scientific research projects on PSC. In addition, the cohort will allow collaborations with reference networks on PSC abroad
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with PSC according to established criteria (European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of cholestatic liver diseases) of any age. Patients not fulfilling such criteria but still diagnosed with PSC in a hepatology referral centre can be included
- •patients living in Switzerland
排除标准
- 未提供
结局指标
主要结局
Transplantation-free survival rate
时间窗: 3 years
Observing transplantation-free survival rate
Overall survival
时间窗: 3 years
Observing overall survival
Disease features
时间窗: 3 years
Observing disease features in Swiss population and see if they are similar to other countries'
Disease course
时间窗: 3 years
Observing disease course
Response to treatment
时间窗: 3 years
Observing response to treatment
次要结局
未报告次要终点