NCT03317704已完成不适用
Regulation of Metabolism and Ion Handling - Effect of High Intensity Training and NAC-infusion in Young Men
Morten Hostrup, PhD2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2017年10月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Quadriceps endurance
研究概览
简要总结
This study investigates the relation between ion-handling (K+) and fatigue development during exercise. Before and after a 6-week period of high intensity interval training, performance and ion-handling is assessed in young adults. In addition, mitochondrial function is examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Healthy men
- •45-55 ml/kg/min
- •BMI 19-26 kg/m2
- •Normal ECG (assessed by MD)
排除标准
- •Allergic to n-acetylcystine (NAC) or digoxin
- •Severe side effects from NAC or digoxin
- •Chronic diseases (assessed by MD to be a potential hazard or to interfere with outcome measures)
结局指标
主要结局
Quadriceps endurance
时间窗: Change from before (baseline) to after 6 weeks of training (Week 6)
Time to exhaustion during knee-extensor exercise
次要结局
- K+ release(Change from before (baseline) to after 6 weeks of training (Week 6))
研究者
Morten Hostrup, PhD
Assistant Professor
University of Copenhagen
研究点 (2)
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