Role of K+ and Ca2+ in Development of Muscle Fatigue

Not Applicable

Completed

• Conditions: Skeletal Muscle Fatigue in Humans
• Interventions: Drug: Terbutaline; Drug: Placebo

• Registration Number: NCT02712658
• Lead Sponsor: University of Copenhagen

Brief Summary

The aim of the study is to investigate the role of K+ and Ca2+ in development of muscle fatigue in trained young men.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2015-10-11
• Primary Completion: 2016-03
• Study Completion: 2016-03
• Study First Submitted QC: 2016-03-17
• Study First Posted: 2016-03-18
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-29
• Last Update Posted: 2017-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• physical active healthy men
• aged 18-40 years

Exclusion Criteria

• smokers
• allergy towards terbutaline
• chronic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
terbutaline	Terbutaline	terbutaline is administered by injection (0.25-0.5 mg Bricanyl, AstraZeneca diluted in 9 ml isotonic saline)
Placebo	Placebo	placebo is administered as isotonic saline (10 ml)

Primary Outcome Measures

Name	Time	Method
Change in time to fatigue during knee-extensor exercise	1 day

Trial Locations

Locations (1)

Department of Nutrition, Exercise and Sports; 🇩🇰 Copenhagen, Denmark