The effect of spironolactone on renal hemodynamics in patients with essential hypertension

niversity clinic of Nephrology and Hypertension, Regional Hospital Holstebro0 个研究点目标入组 20 人开始时间: 2019年5月13日最近更新: 2022年3月28日

适应症

试验速览

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•40-80 years, BMI 18,5-30,0 kg/m2, fertile women must use contraception, hypertension, signed consent form
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 12
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 8

•Alcohol abuse, substance abuse, tobacco smoking, cancer, pregnancy or nursing, diabetes mellitus, GFR < 60 ml/min, Albuminuria > 700 mg/l, clinically significant signs of lung-, liver-, metabolic or neurologic disorders, clinically significant abnormalities in screening blood tests, urine tests or ECG, clinical signs of secondary hypertension, treatment with more than 3 different types of antihypertensives, office blood pressure > 170/105 repeatedly despite regulaion og antihypertensive medicine, donation of blood within one month of the first examination day, uacceptable symptoms due to high blood pressure

发起方

niversity clinic of Nephrology and Hypertension, Regional Hospital Holstebro