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临床试验/NCT07575802
NCT07575802已完成不适用

Lower Limb Muscle Strength and Power Predict Exercise-Induced Prefrontal Hemodynamic Response: An Interpretable Machine Learning Study Using fNIRS Data

Lincoln University College1 个研究点 分布在 1 个国家目标入组 256 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
256
试验地点
1

研究概览

简要总结

This study aims to investigate the predictive value of lower limb muscle strength and explosive power on exercise-induced prefrontal hemodynamic responses. Using an interpretable machine learning framework (GCAT-Net), the research analyzes how various physical performance indicators-such as isokinetic muscle strength, 1RM leg press, and vertical jump metrics-can predict oxygenated hemoglobin (ΔHbO) changes in the bilateral dorsolateral prefrontal cortex (DLPFC) during moderate-intensity cycling.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy adults aged between 18.00 and 60.00 years.
  • Must be able to perform standardized lower-limb physical assessments, including isokinetic strength testing and explosive power tests (e.g., CMJ, SJ, and 30m sprints).
  • Capability to complete a 6-minute aerobic cycling task at a moderate intensity (60% VO_2max).
  • Physically cleared for exercise as determined by a Physical Activity Readiness Questionnaire (PAR-Q).
  • Willingness to undergo functional near-infrared spectroscopy (fNIRS) monitoring with a Scalp Coupling Index (SCI) ≥ 0.7.

排除标准

  • History of musculoskeletal injuries to the lower limbs within the past 6 months that would impede maximum voluntary contraction (MVC) or high-intensity efforts.
  • Known cardiovascular, respiratory, or neurological conditions that contraindicate maximal exercise testing (VO_2max ramp protocol).
  • Body Mass Index (BMI) or health status that prevents the safe completion of high-impact explosive power tests like the 30cm drop jump (RSI assessment).
  • Presence of excessive motion artifacts or poor fNIRS signal quality, specifically a Signal-to-Noise Ratio (SNR) < 5 dB or motion artifact frame ratio ≥$ 10%.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Linjun Liu

Doctoral Researcher

Lincoln University College

研究点 (1)

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