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临床试验/IRCT201205127274N4
IRCT201205127274N4已完成未知

A comparison between corticosteroid injection versus local anaesthetic in treatment of lateral epicondylitis

Vice Chancellor for Research, Guilan University of Medical Sciences0 个研究点目标入组 90 人开始时间: 待定最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
90

研究概览

简要总结

Abstract
Introduction: This study seeks to compare two treatment methods of lateral epicondylitis: corticosteroid injection (CSI) and a local anesthetic injection (LAI).

Materials and methods: In this single-blinded randomized clinical trial, 138 patients with the diagnosis of lateral epicondylitis were assigned either into CSI group receiving methylprednisolone 1 ml (49 patients) or LAI group (51 patients) receiving procaine 1 ml 2 % in a single dose at the maximal point tenderness site. The primary outcome
measure was elbow disability using Quick DASH, and secondary outcome measures were pain intensity using Visual Analogue Scale (VAS) and recurrence rate at pre-treatment visit and at 3-, 6- and 12-week post-treatment visits.

Results: There were no signi?cant differences between the patients in both groups for demographic factors including age, gender, dominant hand, involved hand, and work pressure. Before treatment, the patients in both groups were suffering from the same rates of elbow disability and pain as measured by Quick DASH and VAS, respectively,
(p[0.05). In general, the recovery rate (comparison between pretreatment visit and last post-treatment visit) was signi?cantly more effective and higher in CSI than LAI. CSI was dramatically more effective at 3-week visit, but less and less effective at 6- and 12-week visits. At 12-week visit the recurrence rate was 34.7 % (17 patients) in CSI group.

Conclusion: For lateral epicondylitis, CSI has the best short-term treatment results yet the highest recurrent rates.The combination of CSI with other treatment option or with a change in injection technique from single injection to peppering injection may be promising.

Keywords Tennis elbow Lateral epicondylitis Intra-lesional injection Corticosteroids Local anesthetic, Visual analogue scale Treatment outcome

研究设计

研究类型
Interventional

入排标准

年龄范围
15 years 至 no limit(—)
性别
All

入选标准

  • chronic pain in lateral zone of elbow; definite tenderness in lateral epicondylitis; age more than 15 years and VAS score more than 6. Exclusion criteria: radicular pain to the upper limbs; established Carpal Tunnel Syndrome and past history of tennis elbow treatment.

排除标准

  • 未提供

研究者

发起方
Vice Chancellor for Research, Guilan University of Medical Sciences

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