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Clinical Trials/NCT04887844
NCT04887844
Completed
Not Applicable

Comparison of the Efficacy of Corticosteroid and Local Anesthetic Injections Combined With Conventional Physiotherapy in Patients With Concomitant Pes Anserine Bursitis and Knee Osteoarthritis:

Abant Izzet Baysal University1 site in 1 country102 target enrollmentMarch 1, 2019

Overview

Phase
Not Applicable
Intervention
Lidocaine injection
Conditions
Osteoarthritis Knees Both
Sponsor
Abant Izzet Baysal University
Enrollment
102
Locations
1
Primary Endpoint
Visual analogue scale
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

To evaluate the efficiencies of local corticosteroid injections and local anesthetics in patients with concomitant pes anserine bursitis and osteoarthritis.

Detailed Description

Several treatment options have been tried with varying success rates, including nonsteroidal anti-inflammatory drugs, physiotherapy modalities, cold application with ice-packs, and injection of local anesthetics and/or corticosteroids. Despite a relatively high frequency of this painful condition, surprisingly, few studies have evaluated treatment strategies in randomized controlled study design. To the best of our knowledge, no study in the literature made a comparison of the efficacy of local anesthetic and corticosteroid injections in addition to physiotherapy in the treatment of pes anserine bursitis yet. Thus, we aimed to compare the treatment efficacies of physiotherapy alone, physiotherapy + local anesthetic injection, and physiotherapy + local corticosteroid injection in a randomized controlled study design in patients with concomitant osteoarthritis and pes anserine bursitis.

Registry
clinicaltrials.gov
Start Date
March 1, 2019
End Date
March 15, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mustafa Fatih YAŞAR

Assistant Professor

Abant Izzet Baysal University

Eligibility Criteria

Inclusion Criteria

  • Patients having stage II-IV knee osteoarthritis along with pes anserine bursitis
  • Symptom onset for more than three months

Exclusion Criteria

  • Patients who underwent knee operations
  • had an inflammatory rheumatic disease
  • had a history of knee trauma
  • had a meniscus tear
  • valgus/varus deformity
  • received injection treatment to pes anserine bursa during the preceding year

Arms & Interventions

Group I

34 patients who were diagnosed with concomitant knee osteoarthritis and pes anserine bursitis and met inclusion criteria were included in the study. Inclusion criteria were as follows: having stage II-IV knee osteoarthritis along with pes anserine bursitis, duration of symptoms for more than three months, and age between 20 and 70 years. Primary knee osteoarthritis was diagnosed as per American College of Rheumatology (ACR) criteria and graded via Kellgren-Lawrence radiological classification included in this study.

Intervention: Lidocaine injection

Group II

34 patients who were diagnosed with concomitant knee osteoarthritis and pes anserine bursitis and met inclusion criteria were included in the study. Inclusion criteria were as follows: having stage II-IV knee osteoarthritis along with pes anserine bursitis, duration of symptoms for more than three months, and age between 20 and 70 years. Primary knee osteoarthritis was diagnosed as per (ACR) criteria and graded via Kellgren-Lawrence radiological classification included in this study.

Intervention: Corticosteroid injection

Group III

34 patients who were diagnosed with concomitant knee osteoarthritis and pes anserine bursitis and met inclusion criteria were included in the study. Inclusion criteria were as follows: having stage II-IV knee osteoarthritis along with pes anserine bursitis, duration of symptoms for more than three months, and age between 20 and 70 years. Primary knee osteoarthritis was diagnosed as per (ACR) criteria and graded via Kellgren-Lawrence radiological classification included in this study.

Intervention: Conventional Physical therapy

Outcomes

Primary Outcomes

Visual analogue scale

Time Frame: eight weeks

We used paper-based VAS to evaluate the baseline severity and changes in the intensity of pain by different interventions in the entire study cohort. The visual analogue scale was devised by Hayes and Patterson and is used to document pain rating. Subjects self-report the intensity of their pain by placing a handwritten mark at one point of the length of a ten-centimeter line. The two ends of the scale line represent "no pain" and "worst pain experienced" at the zero cm and 10th cm of the scale, respectively.

Secondary Outcomes

  • Western Ontario and McMaster Universities Osteoarthritis Index(eight weeks)
  • 3-meter walk test(eight weeks)

Study Sites (1)

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