Potential Risk Factors for Postpartum Psychosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 4,000
- 试验地点
- 1
- 主要终点
- Incidence of psychoses
研究概览
简要总结
A range of psychological disorders occur in women in the postpartum period. These include "the blues", which occurs in the first days after birth and which is very common and self-limiting; severe psychoses often associated with mania or bipolar illness, occurring in the first weeks after birth; and mild to moderate depression, occurring weeks to months after birth. Studies have been done focused on postpartum psychosis using a retrospective investigation, which gave only a limited material on the prevalence of psychological disorders in postpartum women. The investigators hypothesized that different pathways to psychosis function as the risk factors which may be overlapped, truly independent, mediating, or moderating, in new mothers who are at high risk and/or during the early period of delivery. In addition, the investigators purposed that the temporal sequence of biological, social and demographic variables are also the potential factors contributing to the development of postpartum psychosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women
排除标准
- •Age < 18 years or > 50 years
- •Gestational age < 32 weeks
结局指标
主要结局
Incidence of psychoses
时间窗: 3 months and 6 months postpartum
次要结局
- Antepartum economic level(One year before labor and delivery (recorded by antepartum communication))
- Antepartum social status(One year before labor and delivery (recorded by antepartum communication))
- Antepartum psychological level(1 day before birth)
- Intrapartum complications(1 day after birth)
- Baby characteristics(One minute, 5min, 15min after baby was born)
- Maternal characteristics(One day after birth)
- Medical caregiver characteristics(One day before and after the labor completion)
- Parturient family characteristics(One week before labor and delivery, recorded by investigators through patients' antepartum communication)
- Intrapartum medical procedures(One day after birth)
研究者
Fu Zhou Wang
Dr
Nanjing Medical University
