IRCT20180722040556N8尚未招募3 期
Curcumin in the prevention of cisplatin-induced acute nephrotoxicity: a randomized,double-blind, placebo-controlled ?clinical trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Creatinine Clearance higher than 45 mL/min based on CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
- •The patient who will have enough compliance and ability to take curcumin orally.
- •All adult cancer 's patients who will receive a regimen contains cisplatin (with the usual recommended dose between 50-100 mg / m2 )
排除标准
- •Patients with active infection or symptoms of sepsis.
- •Patients who have received nephrotoxic drugs such as aminoglycoside, amphotericin, vancomycin, colistin, media contrast, calcineurin inhibitors or Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for the past 72 hours.
- •Patients who are taking ifosfamide in their chemotherapy regimen
- •Patients who are taking fluvoxamine, anagrelide, or hydroxy progesterone in their treatment regimen.
- •Patients who may experience complications or allergic reactions to curcumin during treatment.
- •Patients who had a history of acute kidney injury ( AKI ) before entering the study.
- •Patients with bilirubin above 2 mg / dl or liver enzymes above 2.5 times the normal level.
研究者
相似试验
已完成
3 期
The effect of curcumin on the prevention of paclitaxel and platinum compounds-induced neuropathy in cancer patientsChemotherapy induced neuropathy.IRCT20191106045356N6Yazd University of Medical Sciences35
进行中（未招募）
不适用
Aprepitant in the prevention of cisplatin-induced delayed emesis: a double-blind randomized study - Aprepitant for cisplatin-induced delayed emesisEUCTR2008-001339-37-ITAZIENDA OSPEDALIERA S. MARIA DI TERNI560
尚未招募
3 期
Effect of curcumin on the prevention of contrast induced nephropathyephropathy induced by contrast agents.Nephropathy induced by other drugs, medicaments and biological substancesN14.1IRCT20210413050958N2Mashhad University of Medical Sciences227
尚未招募
3 期
Curcumin effects on the prevention of peripheral neuropathy-induced by chemotherapy regimen containing paclitaxel in breast cancer patients; a randomized, double blinded and placebo-controlled clinical trialIRCT20180722040556N10Esfahan University of Medical Sciences60
已完成
2 期
The effect of curcumin in the prevention of kidney failure following heart angiographyRenal FailureIRCT138706261256N1Vice Chancellor Of Research, Mashad University of Medical Sciences60