跳至主要内容
临床试验/NCT04757454
NCT04757454已完成不适用

Performance Indicators of the SARC-F Questionnaire in Acute Care

Brugmann University Hospital1 个研究点 分布在 1 个国家目标入组 105 人开始时间: 2019年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
105
试验地点
1
主要终点
Overall concordance agreement between the SARC-F questionnaire as a screening method and the gold standard method, which is the EWGSOP2

研究概览

简要总结

The study applies the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire in older patients hospitalized in an acute care geriatric unit and aims to determine its performance indicators to screen for sarcopenia according to the revised European Consensus on definition and diagnosis (EWGSOP2) within this population

详细描述

Sarcopenia is an age-related disease associated with health adverse outcomes, i.e. higher risk of mobility limitation, falls, fractures, mortality, and lower quality of life. The European Working Group on Sarcopenia has recently revisited one of the widely used most acknowledged definitions and launched the revised European consensus on definition and diagnosis (EWGSOP2) (4). Applying the EWGSOP2 is a three-tier process: first, screening by the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire; second, diagnosis by low muscle strength, and low muscle mass; third, severity grading by low muscle function. The EWGSOP2 recommends the assessment of sarcopenia in every population, both in community-dwelling and acute care older patients. However, the evidence about the performance indicators of the SARC-F questionnaire to screen for sarcopenia in acute patients admitted to an acute care unit is really limited.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged 65 and over
  • Hospitalized in an acute care geriatric unit due to acute health issues or acute medical conditions
  • With SARC-F, hand-grip strength and dual-energy X-ray absorptiometry administered during hospital admission

排除标准

  • SARC-F unavailable
  • Unwilling to collaborate in the sarcopenia assessment
  • Unwilling to sign the informed consent

结局指标

主要结局

Overall concordance agreement between the SARC-F questionnaire as a screening method and the gold standard method, which is the EWGSOP2

时间窗: September 2019-November 2020

Cohen-kappa coefficient, measured as a percentage (%)

Sensitivity of the SARC-F questionnaire as screening method compared to the gold standard, which is the revised European consensus on definition and diagnosis

时间窗: September 2019-November 2020

Sensitivity, measured as a percentage (%)

Specificity of the SARC-F questionnaire as a screening method, compared to the gold standard which is the revised European Consensus on definition and diagnosis of sarcopenia (EWGSOP2)

时间窗: September 2019-November 2020

Specificity, measured as a percentage (%)

次要结局

  • Health adverse outcomes based on the screening and diagnosis of sarcopenia as recommended by the EWGSOP2(1-year follow-up)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Murielle Surquin

Head of the Internal Medicine and Geriatrics Department

Brugmann University Hospital

研究点 (1)

Loading locations...

相似试验