Evaluation of the Effectiveness of Crocin of Saffron in treatment of Burning Mouth Syndrome

Mashhad University of Medical Sciences0 个研究点目标入组 50 人开始时间: 待定最近更新: 2018年6月18日

适应症

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•Daily bilateral burning sensation of oral mucosa for at least 4 to 6 months, persistent or increased burning intensity throughout the day, natural oral mucosa in clinical examination and the absence of any local or systemic causes to legitimize the irritation of the mouth, minimum burning intensity of 5 on the VAS scale for patients with BMS, not receiving any antidepressant treatment during the last 4 weeks

•the history of systemic disease characterized by burning mouth including diabetes, severe anemia, hypothyroidism, repetitious reflux or a history of micronutrient deficiency , severe psychological disorders such as severe depression, suicide thoughts and the history of hospitalization in psychiatric hospitals, pregnant patients or ones suspected to be pregnant, reports of any susceptibility to drugs or adverse effects, the use of monoamine oxidase inhibitors, tramadol, beta-blockers, benzodiazepines, tricyclic antidepressants at present or the recent month

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