The Quebec Family Study: an Observational Study Aimed at Investigating the Role of Genetic Factors in Physical Fitness, Obesity and Risk Factors for Common Diseases and Health-related Behaviours
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 951
- 主要终点
- Abdominal fat
研究概览
简要总结
The Quebec Family Study (QFS) is an observational study that was planned to investigate the role of genetic factors in physical fitness, body composition, risk factors for common disease and health-related behaviour.
详细描述
The Quebec Family Study was an observational study with three cycles of data collection between 1978 and 1992. During the first cycle of data collection (Phase 1: 1978-1982), a total of 1,650 subjects from 375 families were recruited. During the second cycle (Phase 2: 1989-1997), 385 subjects from 105 phase 1 families were retested and an additional 372 subject from 74 families were recruited. During the third cycle (Phase 3: 1998-2002), 204 subjects from phase 1 were tested a third time, 113 subjects from phase 2 were tested a second time and 194 new subjects from 44 families were recruited.
研究设计
- 研究类型
- Observational
- 观察模型
- Family Based
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 10 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 10 years
排除标准
- •Not applicable
结局指标
主要结局
Abdominal fat
时间窗: Through study completion, an average of 24 years
Abdominal fat as assessed by commuted tomography
Waist and hip circumferences (cm)
时间窗: Through study completion, an average of 24 years
Waist and hip circumferences (cm)
Body composition
时间窗: Through study completion, an average of 24 years
Body composition as assessed by underwater weighing
Body mass index (kg/m^2)
时间窗: Through study completion, an average of 24 years
Body mass index assessed from height and weight
次要结局
- Physical activity level(Through study completion, an average of 24 years)
- Plasma lipid levels (mmol/L)(Through study completion, an average of 24 years)
- Alcohol consumption(Through study completion, an average of 24 years)
- Caloric intake(Through study completion, an average of 24 years)
- Adiponectin levels (in micrograms/ml)(Through study completion, an average of 24 years)
- Energy expenditure(Through study completion, an average of 24 years)
- Smoking habits (nb of cigarettes per day)(Through study completion, an average of 24 years)
- Blood pressure (mm Hg)(Through study completion, an average of 24 years)
- Glucose levels (mmol/L)(Through study completion, an average of 24 years)
- C-reactive protein (CRP in mg/ml)(Through study completion, an average of 24 years)
- Sleeping (hours/day)(Through study completion, an average of 24 years)
- Eating behaviour(Through study completion, an average of 24 years)
- Insulin levels (pmol/L)(Through study completion, an average of 24 years)
- Interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-alpha) in pg/ml(Through study completion, an average of 24 years)
研究者
Louis Pérusse
Professor
Laval University