Changes of Optical Quality During the Peak of the Covid-19 Pandemic From November 2022 to January 2023 in China
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- The value of cornea thickness
研究概览
简要总结
To explore whether cornea structure, and optical quality are affected by the covid-19 infection.
详细描述
Participants with healthy corneas admitted to Tianjin Eye Hospital from November 25 to January 20, 2022 were followed up . At the end of the follow-up, the investigators recorded in detail whether the patients had undergone real-time reverse transcriptase polymerase chain reaction (covid-19 RT-PCR tests) testing, testing time and results. The presence of PCR-positive during follow-up is considered to be covid-19 infection; PCR-Negative and no symptoms of infection during the follow-up period are considered not infected; participants with symptoms but no PCR test were excluded from the study.Participants were divided into three groups according to the RT-PCR results and the presence or absence of symptoms of infection during follow-up. pentacam (Pentacam HR, Oculus, Wetzlar, Germany) was performed during follow-up and the results were recorded,and the data was statistically managed and compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 32 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •corneal disease;
- •ocular trauma;
- •Pregnant and lactating women;
结局指标
主要结局
The value of cornea thickness
时间窗: 1 months
The value of cornea thickness from pentacam during follow-up were compared, includig the thinnest point, apex of the cornea.
The value of cornea backscatter
时间窗: 1 months
The value of cornea backscatter from pentacam during follow-up were compared, including anterior layer,central layer and posterior
The value of cornea aberration
时间窗: 1 months
The value of aberration data from pentacam during follow-up were compared, including coma, spherical aberration, defocus, and astigmatism
次要结局
未报告次要终点
