跳至主要内容
临床试验/NCT00265499
NCT00265499已完成不适用

Skeletonized Versus Non-Skeletonized Internal Thoracic Artery Harvest for Coronary Artery Bypass Grafting

University of Ottawa1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2005年12月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
48
试验地点
1
主要终点
Intra-operative Internal Thoracic Artery Flow measure prior to coronary anastomoses

研究概览

简要总结

The purpose of this study is to determine whether skeletonization of the internal thoracic artery leads to improved flow, increased length, improved sternal perfusion, and decreased pain and dysesthesia in patients undergoing coronary artery bypass surgery

详细描述

Traditional harvesting of the internal thoracic artery (ITA) for use as a conduit in coronary bypass surgery involves the dissection of a rim of tissue surrounding the artery on either side. Although the benefits of ITA use are well established, there are certain limitations to its routine use. Recent studies, primarily observational, have suggested that skeletonization of the ITA (i.e. harvesting of the ITA alone) may overcome some of these limitations by improving conduit flow, increasing length, and reducing the risk of deep sternal infection in high risk patients. Furthermore, skeletonization of the ITA can potentially preserve intercostal nerves and reduce post-operative pain and dysesthesias associated with ITA harvesting. In order to assess the effects of ITA skeletonization, this is a prospective, randomized, within-patient study design in patients undergoing coronary artery bypass grafting.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Double

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients undergoing bilateral internal thoracic artery harvest for coronary artery bypass surgery

排除标准

  • •Inability to speak English or French
  • •Inability to complete follow-up visits

结局指标

主要结局

Intra-operative Internal Thoracic Artery Flow measure prior to coronary anastomoses

次要结局

  • - Internal Thoracic Artery length
  • - Sternal Perfusion (SPECT imaging)
  • - Post-operative pain and dysesthesia

研究者

申办方类型
Other

研究点 (1)

Loading locations...

相似试验