NCT00157287已完成3 期
A Cluster Randomized Trial to Improve Weaning and Extubation From Mechanical Ventilation in Community Hospitals
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's22 个研究点 分布在 1 个国家开始时间: 2003年6月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 试验地点
- 22
- 主要终点
- ICU length of stay
研究概览
简要总结
Protocol directed weaning has been shown to reduce the duration of mechanical ventilation for patients admitted to the intensive care unit (ICU) of tertiary centres. However, this benefit has not previously been studied in a community hospital setting. We therefore sought to evaluate the impact of an evidence-based weaning guideline on the outcomes for patients receiving mechanical ventilation in the ICUs of community hospitals in a cluster randomized controlled trial involving 11 community hospitals.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients ventilated for more than 24 hours
排除标准
- •patients less than 16 years of age patients who receive only non-invasive ventilation patients chronically ventilated at time of ICU admission patients who will not be candidates for weaning from ventilation at time of admission If withdrawl of life support is imminent at the point the patient has been ventilated for 24 hours
结局指标
主要结局
ICU length of stay
次要结局
- complications (re-intubation within 48 hours, pneumonia within 48 hours)
- Qulaity of life
- duration of ventilation
- ICU mortality
- length of hospital stay
- Hospital mortality
- ICU readmissions
研究者
研究点 (22)
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